Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Isomer-Specific Product Detection Of Cn Radical Reactions With Ethene And Propene By Tunable Vuv Photoionization Mass Spectrometry, Adam Trevitt, Fabien Goulay, Giovanni Meloni, David Osborn, Craig Taatjes, Stephen Leone
Isomer-Specific Product Detection Of Cn Radical Reactions With Ethene And Propene By Tunable Vuv Photoionization Mass Spectrometry, Adam Trevitt, Fabien Goulay, Giovanni Meloni, David Osborn, Craig Taatjes, Stephen Leone
Adam Trevitt
No abstract provided.
Differentiation Of Complex Lipid Isomers By Radical-Directed Dissociation Mass Spectrometry, Huong Pham, Tony Ly, Adam Trevitt, Todd Mitchell, Stephen Blanksby
Differentiation Of Complex Lipid Isomers By Radical-Directed Dissociation Mass Spectrometry, Huong Pham, Tony Ly, Adam Trevitt, Todd Mitchell, Stephen Blanksby
Adam Trevitt
Contemporary lipidomics protocols are dependent on conventional tandem mass spectrometry for lipid identification. This approach is extremely powerful for determining lipid class and identifying the number of carbons and the degree of unsaturation of any acyl-chain substituents. Such analyses are however, blind to isomeric variants arising from different carbon−carbon bonding motifs within these chains including double bond position, chain branching, and cyclic structures. This limitation arises from the fact that conventional, low energy collision-induced dissociation of even-electron lipid ions does not give rise to product ions from intrachain fragmentation of the fatty acyl moieties. To overcome this limitation, we have …
Cyclic Versus Linear Isomers Produced By Reaction Of The Methylidyne Radical (Ch) With Small Unsaturated Hydrocarbons, Adam Trevitt, Talitha Selby, Luc Vereecken, Fabien Goulay, Giovanni Meloni, David Osborn, Craig Taatjes, Stephen Leone
Cyclic Versus Linear Isomers Produced By Reaction Of The Methylidyne Radical (Ch) With Small Unsaturated Hydrocarbons, Adam Trevitt, Talitha Selby, Luc Vereecken, Fabien Goulay, Giovanni Meloni, David Osborn, Craig Taatjes, Stephen Leone
Adam Trevitt
No abstract provided.
Gas-Phase Reactions Of Aryl Radicals With 2-Butyne: An Experimental And Theoretical Investigation Employing The N-Methyl-Pyridinium-4-Yl Radical Cation, Adrian Lam, Cong Li, George Khairallah, Benjamin Kirk, Stephen Blanksby, Adam Trevitt, Uta Wille, Richard O'Hair, Gabriel Da Silva
Gas-Phase Reactions Of Aryl Radicals With 2-Butyne: An Experimental And Theoretical Investigation Employing The N-Methyl-Pyridinium-4-Yl Radical Cation, Adrian Lam, Cong Li, George Khairallah, Benjamin Kirk, Stephen Blanksby, Adam Trevitt, Uta Wille, Richard O'Hair, Gabriel Da Silva
Adam Trevitt
Aromatic radicals form in a variety of reacting gas-phase systems, where their molecular weight growth reactions with unsaturated hydrocarbons are of considerable importance. We have investigated the ion–molecule reaction of the aromatic distonic N-methyl-pyridinium-4-yl (NMP) radical cation with 2-butyne (CH3C≡CCH3) using ion trap mass spectrometry. Comparison is made to high-level ab initio energy surfaces for the reaction of NMP and for the neutral phenyl radical system. The NMP radical cation reacts rapidly with 2-butyne at ambient temperature, due to the apparent absence of any barrier. The activated vinyl radical adduct predominantly dissociates via loss of a H atom, with lesser …
Reaction Of The C2h Radical With 1-Butyne (C4h6): Low Temperature Kinetics And Isomer-Specific Product Detection, Satchin Soorkia, Adam J. Trevitt, Talitha M. Selby, David L. Osborn, Craig A. Taatjes, Kevin R. Wilson, Stephen R. Leone
Reaction Of The C2h Radical With 1-Butyne (C4h6): Low Temperature Kinetics And Isomer-Specific Product Detection, Satchin Soorkia, Adam J. Trevitt, Talitha M. Selby, David L. Osborn, Craig A. Taatjes, Kevin R. Wilson, Stephen R. Leone
Adam Trevitt
No abstract provided.
Reactions Of The Cn Radical With Benzene And Toluene: Product Detection And Low-Temperature Kinetics, Adam J. Trevitt, Fabien Goulay, Craig A. Taatjes, David L. Osborn, Stephen R. Leone
Reactions Of The Cn Radical With Benzene And Toluene: Product Detection And Low-Temperature Kinetics, Adam J. Trevitt, Fabien Goulay, Craig A. Taatjes, David L. Osborn, Stephen R. Leone
Adam Trevitt
Low-temperature rate coefficients are measured for the CN + benzene and CN + toluene reactions using the pulsed Laval nozzle expansion technique coupled with laser-induced fluorescence detection. The CN + benzene reaction rate coefficient at 105, 165, and 295 K is found to be relatively constant over this temperature range, (3.9−4.9) × 10−10 cm3 molecule−1 s−1. These rapid kinetics, along with the observed negligible temperature dependence, are consistent with a barrierless reaction entrance channel and reaction efficiencies approaching unity. The CN + toluene reaction is measured to have a rate coefficient of 1.3 × 10−10 cm3 molecule−1 s−1 at 105 …
Reactions Of Simple And Peptidic Alpha-Carboxylate Radical Anions With Dioxygen In The Gas Phase, Tony Ly, Benjamin B. Kirk, Pramesh I. Hettiarachchi, Berwyck L. Poad, Adam J. Trevitt, Gabriel Da Silva, Stephen J. Blanksby
Reactions Of Simple And Peptidic Alpha-Carboxylate Radical Anions With Dioxygen In The Gas Phase, Tony Ly, Benjamin B. Kirk, Pramesh I. Hettiarachchi, Berwyck L. Poad, Adam J. Trevitt, Gabriel Da Silva, Stephen J. Blanksby
Adam Trevitt
α-Carboxylate radical anions are potential reactive intermediates in the free radical oxidation of biological molecules (e.g., fatty acids, peptides and proteins). We have synthesised well-defined α-carboxylate radical anions in the gas phase by UV laser photolysis of halogenated precursors in an ion-trap mass spectrometer. Reactions of isolated acetate (CH2CO 2-) and 1-carboxylatobutyl (CH3CH 2CH2CHCO2-) radical anions with dioxygen yield carbonate (CO3-) radical anions and this chemistry is shown to be a hallmark of oxidation in simple and alkyl-substituted cross-conjugated species. Previous solution phase studies have shown that Cα-radicals in peptides, formed from free radical damage, combine with dioxygen to form …