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Wright State University

Theses/Dissertations

HSV-1

2017

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Effects Of Myrrh On Hsv-1 Using Plaque Assay, Badrieah Mohammad Alamri Jan 2017

Effects Of Myrrh On Hsv-1 Using Plaque Assay, Badrieah Mohammad Alamri

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Herpes simplex virus type 1 (HSV-1) is a highly infective human pathogen which infects a wide range of population in North America and worldwide. HSV-1 infection has two phases, lytic and latent. Recurrence of HSV-1 is a major challenge to clinicians to control the infection especially in immune depleted individuals. Acyclovir (ACV) is an antiviral drug used to treat HSV-1 infection. Low solubility of ACV in water, mutation of viral thymidine kinase, and mutation of viral DNA polymerase are major problems that cause usage limitations of ACV. Myrrh has been used as an analgesic and anti-inflammatory natural product in middle …