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Full-Text Articles in Life Sciences

Cd28 Costimulation Requirement For Interferon-Y Secretion By Natural Killer T Cells During Hepatitis B Virus Infection, Paul J. Renick Jan 2002

Cd28 Costimulation Requirement For Interferon-Y Secretion By Natural Killer T Cells During Hepatitis B Virus Infection, Paul J. Renick

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Natural Killer T cells (NKT cells) are a unique subset of lymphocytes that express natural killer (NK) and T cell receptors (TCR). The NKT cell population includes four separate subclasses. This paper will focus on Category I NKT cells which possess a canonical TCR receptor (Va14Ja281) that recognizes only hydrophobic antigens presented by CD1d molecules. These cells are believed to play an important regulatory role in immunity. A variety of disease conditions, including cancer, infections and Type I diabetes, are controlled by NKT cells. NKT cells are also capable of secreting large quantities of cytokines, namely interleukin-4 (IL-4) and interferon-gamma …


Using Ecological Land Units In A Gap Analysis For Conservation Planning In A Southwestern Ohio Watershed, Christopher Lee Zimmerman Jan 2002

Using Ecological Land Units In A Gap Analysis For Conservation Planning In A Southwestern Ohio Watershed, Christopher Lee Zimmerman

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Gap analysis is a method to identify insufficiency in biodiversity protection. In degraded agricultural landscapes, it requires information on the past, present, and the potential natural distribution of forest vegetation to construct a comprehensive nature reserve network. Using Geographic Information Systems (GIS), I conducted a biodiversity gap analysis to assess the representation of ecological land units (ELUs) supporting forest vegetation both within and external to the current reserve network in the Lower Twin Creek Watershed (LTCW), southwestern Ohio. I used this analysis to make conservation planning recommendations to the local park district. ELUs are based on relatively stable associations of …