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Full-Text Articles in Life Sciences

Identification Of Axon-Oligodendrocyte Preferential Interaction Sites Preceding Initial Myelin Sheath Formation, Taryn Mallon, Rachael Sawyer Apr 2018

Identification Of Axon-Oligodendrocyte Preferential Interaction Sites Preceding Initial Myelin Sheath Formation, Taryn Mallon, Rachael Sawyer

Undergraduate Research Celebration 2018

Oligodendrocytes are matured oligodendrocyte progenitor cells that serve to myelinate axons within the central nervous system. The myelination process is complex and is orchestrated by many unknown mechanisms, of particular interest, the causal relationship between axon diameter and myelination. Previous studies suggest that oligodendrocytes preferentially myelinate axons with larger diameters. Due to the variation in axon diameter along the length of individual axons, we first hypothesized that oligodendrocytes interact with and initiate myelination at thicker domains of axons known as varicosities. To test this hypothesis, we performed in vivo time-lapse in zebrafish larvae to determine if oligodendrocytes preferentially interact with …


Development Of A Pcr For Simultaneous Amplification Of Borrelia Burgdorferi And Ixodes Tick Dna, Shaynee Studer, Alina Yevsina Apr 2018

Development Of A Pcr For Simultaneous Amplification Of Borrelia Burgdorferi And Ixodes Tick Dna, Shaynee Studer, Alina Yevsina

Undergraduate Research Celebration 2018

The high prevalence of Ixodes ticks in Southeast Minnesota has serious implications as they are often vectors for infectious tick-borne agents, such as Borrelia burgdorferi, the causative agent of Lyme Disease (LD). Currently, our lab has developed a PCR that can amplify Borrelia DNA in infected ticks, however, when ticks fail to amplify it is unclear whether this is from lack of the bacterial agent or if the DNA is corrupted. A possible solution to this problem is to concurrently amplify a gene within the Ixodes tick in order to assess the quality of the DNA. The goal of this …


West-Nile Virus Replicon Particles Infect 293t Cells Expressing Dc-Signr, Osvaldo Martinez, Emin Budimlic, John Keilty, Hannah Kunkel, Wells Pollock, Madilyn R. Schmitz, Nicole Crowson, Nathan L. Leonard, Amanda Madigan, Victoria R. Schwarzinger, Alyssa J. Meyer, Mary Soderlund, Jean K. Lim, Icann School Of Medicine, New York Apr 2018

West-Nile Virus Replicon Particles Infect 293t Cells Expressing Dc-Signr, Osvaldo Martinez, Emin Budimlic, John Keilty, Hannah Kunkel, Wells Pollock, Madilyn R. Schmitz, Nicole Crowson, Nathan L. Leonard, Amanda Madigan, Victoria R. Schwarzinger, Alyssa J. Meyer, Mary Soderlund, Jean K. Lim, Icann School Of Medicine, New York

Undergraduate Research Celebration 2018

West-Nile virus (WNV) is an arbovirus usually transmitted to humans via a mosquito vector. Infections commonly result in febrile symptoms while rare severe neuroinvasive cases may result in encephalitis or meningitis. Studies have shown that WNV infection efficiency is enhanced by expression of DC-SIGNR on target cells, which normally do not express DC-SIGNR. To investigate WNV tropism, we established 293T kidney epithelial cell lines that stably express vector, DC-SIGNR and mutants of DC-SIGNR that lack the entire carbohydrate-recognition domain (CRD) or lack the C-terminal half of the CRD. We demonstrate successful surface expression of DC-SIGNR and its mutants from stablytransfected …


Research Of White Sucker Cell Lines And Associated Viruses, Mohamed Mohamed, Casey M. Finnerty Apr 2018

Research Of White Sucker Cell Lines And Associated Viruses, Mohamed Mohamed, Casey M. Finnerty

Undergraduate Research Celebration 2018

Catostomus commersonii, also known as the White Sucker, is a vital part of most aquatic ecosystems in the U.S. Specifically looking at the Upper Midwest, these fish are widely distributed around the states of Minnesota and Wisconsin. The importance of these organisms is due to their species reputation, they are indicator species that are very useful in informing whether the environment around them is healthy or if contamination has occurred. To better understand the organism, we needed to start at the molecular level. Understanding the nature of White Sucker cells through cell cultures. To get the individual fins of the …


Effect Of A Pre-Dinner Walnut Snack On Nutrient Intake Among University Students, Michelle E. Lacasse, Mackenzie J. Weis, Lauren S. Devaan, Gabrielle L. Schnellman, Elizabeth M. Gile, Molly D. Ahmann, Ted Wilson, Tisha L. Hooks Apr 2018

Effect Of A Pre-Dinner Walnut Snack On Nutrient Intake Among University Students, Michelle E. Lacasse, Mackenzie J. Weis, Lauren S. Devaan, Gabrielle L. Schnellman, Elizabeth M. Gile, Molly D. Ahmann, Ted Wilson, Tisha L. Hooks

Undergraduate Research Celebration 2018

No abstract provided.


Water Quality Of Gilmore Creek In Winona, Minnesota, Megan Diesslin Apr 2018

Water Quality Of Gilmore Creek In Winona, Minnesota, Megan Diesslin

Undergraduate Research Celebration 2018

No abstract provided.


The Influence Of Flower Color On The Foraging Selection Of The Julia Butterfly, Dyras Uilia, In A Captive Habitat At The Minnesota Zoo, Terese Zahradka Apr 2018

The Influence Of Flower Color On The Foraging Selection Of The Julia Butterfly, Dyras Uilia, In A Captive Habitat At The Minnesota Zoo, Terese Zahradka

Undergraduate Research Celebration 2018

No abstract provided.