Life Sciences Commons^™

Autosomal Recessive Forms Of Limb-Girdle Muscular Dystrophy, David N. Catlett

Mahurin Honors College Capstone Experience/Thesis Projects

Limb-girdle muscular dystrophy is a rarely occurring disease not recognized in the past as a distinct entity. Prior to the advent of sophisticated molecular biology techniques in the early I 990s, precise diagnosis of the disease was impossible. However, identification of the altered proteins and underlying genetic defects has brought limb-girdle muscular dystrophy to the forefront of recent biomedical research. Many articles concerning the investigation into limb-girdle muscular dystrophy have been published in genetic and neuromuscular journals since 1992. These fmdings are individually significant, but only a few publications have compiled the results into a comprehensive article relating all past …