Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
The Effect Of Short-Term Supplementation Of Potato Starch And Vsl#3 On The Large Intestines Of Male C57bl/6 Mice, Kaitlyn R. Merz
The Effect Of Short-Term Supplementation Of Potato Starch And Vsl#3 On The Large Intestines Of Male C57bl/6 Mice, Kaitlyn R. Merz
Wayne State University Theses
The microbiome is extremely complex and presumed to be involved in several biological processes. Dysbiosis is associated with development of several diseases, therefore, eubiosis is essential for prevention and treatment, possibly achieved through prebiotic or probiotic supplementation. The objective of this study was to establish effects of short-term supplementation on large intestine microbiota, pH and inflammatory cytokines. Large intestines of 21 day old C57BL/6 male mice that were given a control diet or supplemented with 10% potato starch or VSL#3 short-term, were analyzed for shifts in bacteria, pH, and inflammatory cytokine concentration. Large intestine digesta bacteria concentration differed from feces …
Exploring The Short-Term Effects Of Probiotic And Prebiotic Supplementation On The Microbiota And Physiology Of Male C57bl/6 Mice, Miguel Angel Rivas
Exploring The Short-Term Effects Of Probiotic And Prebiotic Supplementation On The Microbiota And Physiology Of Male C57bl/6 Mice, Miguel Angel Rivas
Wayne State University Theses
The gut microbiome may play a role in the development of chronic diseases like obesity, diabetes, and heart disease. Diets including prebiotics or probiotics can alter the abundance of gut bacterial groups and have subsequent health effects. In this study we wanted to establish a method for comparing the benefits of commercial supplements that alter the microbiota by monitoring fecal microbial profiles in male C57BL/6 mice (n = 24) exposed to 15 days of dietary supplementation. A probiotic diet (VSL#3) and a prebiotic diet (potato starch) were compared to a standard diet (n = 8 for each group). Microbial profiles …