Life Sciences Commons^™

Hepatic Ornithine Metabolism In Hydrazine-Treated Rats, Van Saxton Hubbard

Theses and Dissertations

Ornithine plays an important role in mammalian intermediary metabolism. Ornithine can be (1) utilized as a component of the urea cycle, (2) decarboxylated to form putrescine, a precursor of the polyamines, spermidine and spermine, and (3) converted metabolically to arginine, proline and glutamate. In prior investigations conducted in our laboratories and others, free endogenous hepatic pools of ornithine were found to be elevated following hydrazine administration. Consequently, time-course alterations of arginase, ornithine δ-transaminase, ornithine transcarbamylase, and ornithine decarboxylase activities were investigated regarding the effect of hydrazine treatment on hepatic ornithine metabolism in the rat. As an outgrowth of these investigations, …

Activation Of The Gamma Motor System In The Cat Following Selective Stimulation Of The Motor Cortex And The Pyramidal Tract, James Elliott Forbes

Theses and Dissertations

Until the mid to late 1800's, the cerebral hemispheres were considered to be only the sites of mentation and intellectual activity. On the basis of his observations of epileptic patients, HughIings Jackson (cited from Walshe, l935a) theorized that the cerebral hemispheres were also sites of motor control and sensory experience. The electrical excitability of the cerebrum was first demonstrated by Fritsch and Hitzig in 1870. Since then the motor representation of the various muscles has been mapped out and the types of movement in response to stimulation of the motor cortex and the pyramidal tract have been thoroughly studied.

Mammalian …

The Two-Way Mixed Model Analysis Of Variance, Kenneth Davis Buckley

Theses and Dissertations

The analysis of variance for experiments where the fixed effects or random effects model is appropriate is generally agreed upon with regard to testing procedures and covariance structure. It is only in experiments involving both random and fixed factors, i.e. mixed effects models, that controversy occurs as to the proper analysis. The mixed effect model has been considered by many statisticians, and several techniques have been developed for explaining its structure and performing its analysis for balanced data sets. The relationship of these techniques have been discussed in several papers as well.

The simplest case of the difficulties presented by …