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Cellular Immunity In Children With Down Syndrome (Trisomy-21), Roger Lee Noble
Cellular Immunity In Children With Down Syndrome (Trisomy-21), Roger Lee Noble
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Individuals with Down syndrome (US) suffer from increased incidence of respiratory infections and lymphoblastic leukemia, and a death rate that is particularly high in the first 5 years of life. Relatively few studies have probed immune parameters in young US children. Primary immune defects in DS may be masked by a degree of immune maturity in adults, and hygienic factors may have an effect on immune capability throughout the years. A study of young children can give clearer evidence of the actual primary immune defects in DS.
Blood samples were drawn from 20 DS children under 6 years old and …