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Full-Text Articles in Life Sciences
High-Throughput Rna Sequencing Of Pseudomonas-Infected Arabidopsis Reveals Hidden Transcriptome Complexity And Novel Splice Variants, Brian E. Howard, Qiwen Hu, Ahmet Can Babaoglu, Manan Chandra, Monica Borghi, Xiaoping Tan, Luyan He, Heike Winter-Sederoff, Walter Gassmann, Paola Veronese, Steffen Heber
High-Throughput Rna Sequencing Of Pseudomonas-Infected Arabidopsis Reveals Hidden Transcriptome Complexity And Novel Splice Variants, Brian E. Howard, Qiwen Hu, Ahmet Can Babaoglu, Manan Chandra, Monica Borghi, Xiaoping Tan, Luyan He, Heike Winter-Sederoff, Walter Gassmann, Paola Veronese, Steffen Heber
Biology Faculty Publications
We report the results of a genome-wide analysis of transcription in Arabidopsis thaliana after treatment with Pseudomonas syringae pathovar tomato. Our time course RNA-Seq experiment uses over 500 million read pairs to provide a detailed characterization of the response to infection in both susceptible and resistant hosts. The set of observed differentially expressed genes is consistent with previous studies, confirming and extending existing findings about genes likely to play an important role in the defense response to Pseudomonas syringae. The high coverage of the Arabidopsis transcriptome resulted in the discovery of a surprisingly large number of alternative splicing (AS) events …
Use Of Exposure History To Identify Patterns Of Immunity To Pneumonia In Bighorn Sheep (Ovis Canadensis), Raina K. Plowright, Kezia R. Manlove, E. Frances Cassirer, Paul C. Cross, Thomas E. Besser, Peter J. Hudson
Use Of Exposure History To Identify Patterns Of Immunity To Pneumonia In Bighorn Sheep (Ovis Canadensis), Raina K. Plowright, Kezia R. Manlove, E. Frances Cassirer, Paul C. Cross, Thomas E. Besser, Peter J. Hudson
Wildland Resources Faculty Publications
Individual host immune responses to infectious agents drive epidemic behavior and are therefore central to understanding and controlling infectious diseases. However, important features of individual immune responses, such as the strength and longevity of immunity, can be challenging to characterize, particularly if they cannot be replicated or controlled in captive environments. Our research on bighorn sheep pneumonia elucidates how individual bighorn sheep respond to infection with pneumonia pathogens by examining the relationship between exposure history and survival in situ. Pneumonia is a poorly understood disease that has impeded the recovery of bighorn sheep (Ovis canadensis) following their widespread extirpation in …