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Calcospherite (Calcification Nodule) Size In The Short Rib Polydactyly Syndromes, Helen E. Gruber, Ralph S. Lachman
Calcospherite (Calcification Nodule) Size In The Short Rib Polydactyly Syndromes, Helen E. Gruber, Ralph S. Lachman
Scanning Microscopy
The short rib polydactyly syndromes (SRP) are lethal neonatal skeletal dysplasias with a narrow chest, short limbs, and other abnormalities. Type II (Majewski) short rib polydactyly can be distinguished from the Type I/III (Saldino-Noonan) type on the basis of radiographic and histologic changes. Our previous transmission electron microscopic studies suggested unusual patterns of cartilage calcification in these syndromes. We evaluate calcification in the present study using scanning electron microscopy and quantitative morphometry of calcification regions digested to expose calcospherite nodules (calcification nodules), distinctive morphologic structures which form during cartilage calcification. Mean calcospherite area of the Majewski Type II SRP (3.5 …
Bladder Stone In A Human Female: The Case Of An Abnormally Located Intrauterine Contraceptive Device, Saeed R. Khan, Edward J. Wilkinson
Bladder Stone In A Human Female: The Case Of An Abnormally Located Intrauterine Contraceptive Device, Saeed R. Khan, Edward J. Wilkinson
Scanning Microscopy
A single 4.7 x 3.3 x 1.5 cm solid nodule was removed from the bladder of a 24 years old white female who had lost an intrauterine contraceptive device (IUD) installed approximately four years ago. The nodule showed no external evidence of an IUD or its string. An examination of the nodular surface by scanning electron microscopy (SEM) showed mostly amorphous material with some adherent filamentous structures. Its energy dispersive x-ray microanalysis revealed the presence of calcium and phosphorus suggesting that the nodule was actually a urolith. Fracturing the nodule exposed an embedded entity consistent with being a copper IUD. …