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Helium Quality Affects Thermal Desorber Calibration, Joseph F. Romagnano, Bruce Bugbee

Techniques and Instruments

Thermal desorption technology increases the sensitivity of gas chromatography, but it also can concentrate contaminants from any gas stream that passes over a trap.

If contaminants interfere with the elution of the compound of interest, it is impossible to get a clean blank run (no sample applied yet there is still a peak) and the calibration curve will not pass through zero. This may be the result of contamination in either the gases used to blend the standards (trap tubes) or gases used internally by desorber (cold trap). However, when combined with an inability to get a clean zero, the …