Life Sciences Commons^™

Microbial Lag Phase Can Be Indicative Of, Or Independent From, Cellular Stress, Philip G. Hamill, Andrew Stevenson, Phillip E. Mcmullan, James P. Williams, Abiann D. R. Lewis, Sudharsan S., Kath E. Stevenson, Keith D. Farnsworth, Galina Khroustalyova, Jon Y. Takemoto, John P. Quinn, Alexander Rapoport, John E. Hallsworth

Biology Faculty Publications

Measures of microbial growth, used as indicators of cellular stress, are sometimes quantified at a single time-point. In reality, these measurements are compound representations of length of lag, exponential growth-rate, and other factors. Here, we investigate whether length of lag phase can act as a proxy for stress, using a number of model systems (Aspergillus penicillioides; Bacillus subtilis; Escherichia coli; Eurotium amstelodami, E. echinulatum, E. halophilicum, and E. repens; Mrakia frigida; Saccharomyces cerevisiae; Xerochrysium xerophilum; Xeromyces bisporus) exposed to mechanistically distinct types of cellular stress including low water activity, …