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Utah State University

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

1994

Communication

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Study Of Circulating Antibodies To Heat-Shock Proteins 60 And 70 In Autistic Subjects, Fang-Yi Chiu May 1994

Study Of Circulating Antibodies To Heat-Shock Proteins 60 And 70 In Autistic Subjects, Fang-Yi Chiu

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Autism is a behavioral syndrome characterized by a severe impairment of reciprocal social relations, and of verbal and nonverbal communications. Many different etiologic factors such as viral infection and genetic predisposition have been proposed to explain the development of this disorder. Immune abnormalities, such as a decreased lymphoblastic response to T-cell mitogen, defective antibody responses to rubella vaccine, and decreased numbers of T lymphocytes, also have been identified in a subpopulation of patients with autism, which implies that the development of autism in some cases may be due to autoimmune mechanisms.

Recent evidence suggests that immune response to the heat-shock …