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University of the Pacific

Theses/Dissertations

1978

Melatonin

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The Effects Of Melatonin Injection On Glucose Tolerance In Intact And Pinealectomized Laboratory Rats, Dennis Dale Bruno Jan 1978

The Effects Of Melatonin Injection On Glucose Tolerance In Intact And Pinealectomized Laboratory Rats, Dennis Dale Bruno

University of the Pacific Theses and Dissertations

Studies on rat islet preparations have shown melatonin inhibits MAO activity and thereby reduces glucose mediated insulin release. The objective of this work is to investigate the effects of melatonin on insulin release, and on glucose mediated insulin release in the intact and in the pinealectomized rat.