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Full-Text Articles in Life Sciences

Effective Population Size: Biological Duality, Field & Molecular Approaches, Sarah A. A. Woodin, Michael Grove, Daniel D. Heath Jan 2000

Effective Population Size: Biological Duality, Field & Molecular Approaches, Sarah A. A. Woodin, Michael Grove, Daniel D. Heath

Biological Sciences Publications

No abstract provided.


Skh1, The Mek Component Of The Mkh1 Signaling Pathway In Schizosaccharomyces Pombe, R. Loewith, Andrew V. Hubberstey, D. Young Jan 2000

Skh1, The Mek Component Of The Mkh1 Signaling Pathway In Schizosaccharomyces Pombe, R. Loewith, Andrew V. Hubberstey, D. Young

Biological Sciences Publications

Skip to Next Section We previously reported the identification of Mkh1, a MEK kinase in Schizosaccharomyces pombe that is required for cell wall integrity, and we presented genetic evidence that Pmk1/Spm1, a MAP kinase, functions downstream from Mkh1 in the same pathway. Here, we report the identification of Skh1, a MEK (MAP kinase kinase) in S. pombe. The sequence of Skh1 is nearly identical to that of the recently reported Pek1 sequence. We present biochemical and genetic evidence that Skh1 is the MEK component of the Mkh1-Spm1 MAP kinase cascade. Our yeast two-hybrid results indicate that Mkh1, Skh1, and Spm1 …


Survival And Growth Of Mussels Subsequent To Hemolymph Sampling For Dna, J. F. Yanick, Daniel D. Heath Jan 2000

Survival And Growth Of Mussels Subsequent To Hemolymph Sampling For Dna, J. F. Yanick, Daniel D. Heath

Biological Sciences Publications

No abstract provided.


The Spatial Response Of Male Hooded Warblers To Edges In Isolated Fragments, Ryan D. Norris, Bridget J.M. Stutchbury, Trevo E. Pitcher Jan 2000

The Spatial Response Of Male Hooded Warblers To Edges In Isolated Fragments, Ryan D. Norris, Bridget J.M. Stutchbury, Trevo E. Pitcher

Biological Sciences Publications

We tested whether Hooded Warblers (Wilsonia citrina) avoided abrupt forest edges by radiotracking males breeding in small, isolated forest patches (0.5–2.0 ha) in northwest Pennsylvania. Because territory edges were synonymous with abrupt forest edges in all cases, we compared space use patterns with males radiotracked in a nearby continuous forest (150 ha), where we defined edge from territorial boundaries. Based on the proportion of edge to core area, males in both habitats avoided the area within 20 m of the edge, implying that males responded to the presence of territory edge rather than forest edge. Surprisingly, however, males in isolated …


Adenine Nucleotide Translocase Expression Undergoes Dynamic Regulation During Gastrulation In Xenopus Laevis (Accession # Af231347), Michael J. Crawford, Farhad Khosrowshahian, Richard A. Liversage, Susannah L. Varmuza Jan 2000

Adenine Nucleotide Translocase Expression Undergoes Dynamic Regulation During Gastrulation In Xenopus Laevis (Accession # Af231347), Michael J. Crawford, Farhad Khosrowshahian, Richard A. Liversage, Susannah L. Varmuza

Biological Sciences Publications

We report the isolation and characterization of the Xenopus homolog to human T1 ANT (adenine nucleotide translocase) The 1290 nucleotide sequence contains initiation and termination signals, and encodes a conceptual protein of 298 amino acids. The sequence shares high amino acid identity with the mammalian adenine translocases. The transcript is present in unfertilized eggs, and it is expressed at higher levels during formation of the antero-posterior dorsal axis in embryos. Although low levels are expressed constitutively except in endodermal cells, ANT expression is dynamically regulated during neurulation. At this stage expression in ectoderm rapidly diminishes as the neural folds form, …


Mechanical Modeling Of Tibial Axial Accelerations Following Impulsive Heel Impact, David M. Andrews, Jj Dowling Jan 2000

Mechanical Modeling Of Tibial Axial Accelerations Following Impulsive Heel Impact, David M. Andrews, Jj Dowling

Human Kinetics Publications

A fourth order mass/spring/damper (MSD) mechanical model with linear coefficients was used to estimate axial tibial accelerations following impulsive heel impacts. A generic heel pad with constant stiffness was modeled to improve the temporal characteristics of the model. Subjects (n = 14) dropped (~5 cm) onto a force platform ­(3 trials), landing on the right heel pad with leg fully extended at the knee. A uni-axial accelerometer was mounted over the skin on the anterior aspect of the medial tibial condyle inferior to the tibial plateau using a Velcro™ strap (normal preload ~45 N). Model coefficients for stiffness (k1, k2) …