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An Analysis Of The Effect Of Ss-Hydroxy-Ss-Methylbutyrate On The Flight Ability And Lifespan Of Drosophila Melanogaster, Alexandra Elizabeth Beattie
An Analysis Of The Effect Of Ss-Hydroxy-Ss-Methylbutyrate On The Flight Ability And Lifespan Of Drosophila Melanogaster, Alexandra Elizabeth Beattie
Graduate College Dissertations and Theses
As muscle function deteriorates with age, the discovery of new ways to enhance the quality of human life by stunting inevitable aging processes, such as sarcopenia, is a subject of great interest to aging populations, to health care professionals and to nutritional companies. β-hydroxy-β-methylbutyrate (HMB) enhances muscle strength in humans and attenuates disease-induced and disuse-dependent atrophy in rodents. We investigated the feasibility of utilizing Drosophila as a model organism to study the biological effects of HMB in aging muscle. Using flight ability as an index of muscle function and monitoring the lifespan of flies, we found that normal food supplemented …