Life Sciences Commons^™

Practical Solutions To The Invasion Of Lionfish In Utila, Honduras: Science, Education, Food, And Jewelry, Carolyn Corley

Undergraduate Honors Theses

Lionfish (Pterois sp.) are invasive species capable of devastating coral reef ecosystems due to their lack of predators, large appetites, generalist diet, high fecundity, and rapid spawning rates. As lionfish have expanded their distribution across the Caribbean, many conservation groups have taken it upon themselves to systematically remove these predators from environments where they are threatening native species. However, few have involved the community the way I observed while interning with the Whale Shark and Oceanic Research Center in Utila, Honduras. Protecting coral reefs is extremely important, especially in small communities like Utila, where the majority of people’s …

Demystifying The Mind-Body Connection: The Neuroscience Behind How Thoughts Impact Physical Health, Sofia Pantis

Undergraduate Honors Theses

The beliefs, emotions, and experiences that constitute a mindset shape numerous aspects of one’s reality, but in particular, health. Health is defined by not only the physical state of one’s body, but also the content of one’s mind. The integration of the mind and body is often associated with naturopathic medicines or pseudoscience, and thus is usually left out of Western medicinal practices. This review aims to demystify the mind-body connection in health and wellness by introducing it within an empirical, neuroscientific landscape. This research supports the hypothesis that mind over matter rings true even at the biochemical level. Activation …

Diverse Community Of Arsenic Resistant Bacteria Display Arsenate Reducing Capabilities, Stephanie Maeda

Undergraduate Honors Theses

Naturally found in soil and water environments arsenic is toxic to many organisms, carcinogenic to humans, and poses a significant public health risk. Yet communities of bacteria found thriving in arsenic ridden environments have evolved mechanisms to tolerate and exploit both oxidation states of this heavy metal (arsenite and arsenate). As the site of an old arsenic mine, Black Mountain Open Space Park in San Diego, California has yielded concentrations of arsenic in the soil between 111-14,800 ppm. Exceeding average arsenic soil concentrations and levels considered safe in the environment by the World Health Organization, we sought to characterize the …

La Habana: A History Of Society, Livelihood, Movement, And Land Use On The Iquitos-Nauta Highway, Katie Brown

Undergraduate Honors Theses

With increasing infrastructural projects and land titling in the Peruvian Amazon, many changes are occurring within small roadside communities. In this case study, we investigate how these changes impact livelihoods, land use, travel patterns, and social relations within the broader concepts of development, privatization of land, and commodification of nature. Specifically we focus on the caserío La Habana situated on the Iquitos-Nauta highway in the Loreto region of Peru. Semi-formal interviews and ethnographic methods were conducted to gather information on social organization, history of the community, land use practices, migration patterns, opinions on the road, and livelihood strategies. After data …

Sleep Modifications In A Drosophila Melanogaster Model Of Fragile X Syndrome, Morgan Mclaughlin

Undergraduate Honors Theses

Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by intellectual disabilities, disruptions in sleep, and autism in humans. Mutations in Fragile X Mental Retardation gene 1 (FMR1), which codes for a protein that modifies the expression of many target proteins, are primarily responsible for this disorder. Genetic modifications of FMR1 can increase or decrease the overall amount of sleep in humans. A potential pharmaceutical target of FXS is dopamine, a critical neurotransmitter in the regulation of sleep and wakefulness. In fruit flies (Drosophila melanogaster) dopamine has been shown to alter sleep. The mushroom body, a structure in …

The Role Of Dopamine In Decision Making Processes In Drosophila Melanogaster, Michelle C. Bowers

Undergraduate Honors Theses

Understanding the neural processes that mediate decision making is a relatively new field of investigation in the scientific community. With the ultimate goal of understanding how humans decide between one path and another, simpler models such as Drosophila Melanogaster, the common fruit fly, are often utilized as a way of determining the neural circuits involved in these decision-making processes. One of the most important decisions flies make is the decision of where to lay their eggs (oviposit). Choosing the proper substrate upon which to lay eggs is a crucial decision that can ultimately impact their fecundity. This paper investigates the …

To Dust You Shall Return: A Theological Argument For The Human Compost Movement, Sydney N. Ederer

Undergraduate Honors Theses

This research paper analyzes Catholic, Daoist, and Jewish beliefs on death, the body, the soul, afterlife, and after death rituals in order to build a connection between these beliefs and human composting practices. It uses these three religious traditions to find support for and recognize potential opposition against the human compost movement. These conclusions are in turn used to make a claim for human composting. Thorough research and a careful analysis of religious beliefs and traditions surrounding death and the body provides theological support for human composting as a recommended method for body disposal after death. Therefore, this research is …

The Physiological Effects Of Exercise On California Yellowtail (Seriola Dorsalis) White Muscle, Julie Giannini

Undergraduate Honors Theses

California yellowtail (Seriola dorsalis) is a species of ray-finned fish that demonstrates a significant increase in muscle mass in response to sustained exercise at optimal swimming speed. In this study, three groups of yellowtail have been analyzed for a 6-month period to determine if the length of exercise affects white muscle fiber development and if these changes persist when the exercised fish have been returned to a normal “resting” condition. Gene analysis was performed to test if MyoD, a myogenic regulatory factor, was upregulated in response to exercise. To test these questions, the groups compared included a control …

Effect Of Adult Chemical Cues On Molting Of Fiddler Crab Megalopae In Low Salinity Seawater, Sydney Rilum

Undergraduate Honors Theses

Three species of fiddler crabs, Uca minax, U. pugnax, and U. pugilator, are commonly found in estuaries along the Atlantic coast, each with distinct adult habitats differing in salinity and sediment grain size. Prior research has found evidence for larvae exhibiting selective settlement; however, the degree to which and the method by which they choose their species-appropriate habitat to settle in is still unknown. Additionally, a recent study determined that chemical cues from adult crabs stimulate molting in field-caught fiddler crab megalopae, as previously determined in lab-reared megalopae; however, in 35 ppt seawater, few U. minax molted. …

Daphnia: A Possible Way To Combat A Deadly Amphibian Pathogen, Taylor Thomas

Undergraduate Honors Theses

Globally there is a biodiversity crisis, with many groups of species threatened with extinction due to changes in the environment and human impacts. Amphibians are one such group and according to the IUCN, over 30% of amphibians are threatened by extinction. There are many factors have that can explain the decline of amphibians including pollution, habitat loss, climate change and disease. One factor is chytridiomycosis, an emerging infectious disease caused by the chytrid Batrachochytrium dendrobatidis. The chytrid enters the keratinized skin of the amphibian and asexually reproduces, where it disrupts host functions, often leading to host death.

Due to …

2d Nmr Structural Study Of A Dna Duplex Containing Two Unnatural Base Pairs, Weston Preising

Undergraduate Honors Theses

DNA is the genetic blueprint responsible for the traits of living organisms. The "genetic alphabet" consists of four molecules called nucleobases, represented by the letters A, T, G, and C strung together in a "strand." A DNA duplex consists of two "strands" held together such that A is across from T and G across from C, referred to A-T and G-C "base pairs". Recently, the genetic alphabet or code has been expanded by synthetic biologists in an effort to unveil new insights to the machinery of DNA replication, and potentially develop new medicines to cure diseases like HIV. The new …

Investigation Into The Mechanism Of Ion Transport In Rio Negro Characiformes, Vineza D. Reduta

Undergraduate Honors Theses

Four fish species within the Characiform Order [(Rosy tetras (Hyphessobrycon rosaceus), Serpae tetras (Hyphessobrycon eques), Emperor tetras (Nematobrycon palmeri) and Penguin tetras (Thayeria obliqua)] are native to the ion-poor, acidic waters of the Rio Negro. In this paper, we focus on Wood’s revised Na⁺/NH₄⁺ exchange model to gain better insight into the mechanisms of ion transport within the Characids. We exposed each species to two experimental treatments: (i) 1mM ammonia (high external ammonia [HEA]), to test coupling of Na⁺ uptake and ammonia excretion, and (ii) 100μM Acetazolamide …

Examining The Neuronal Dopaminergic Pathway Underlying Sleep Behavior And Related Dopamine Sleep Disorders, Mary Beth Putz

Undergraduate Honors Theses

The human brain is an extremely complex organ with approximately 100 billion different neurons that are constantly sending and receiving messages. These messages are sent using the chemical messengers of the brain: neurotransmitters and neuromodulators. Mechanisms of neural control of sleep are substantially conserved across species. Evidence from multiple animal models including flies, zebrafish, and mice shows that the arousal, or wake phase, is regulated by conserved neuromodulators such as dopamine, norepinephrine, and serotonin. Since these neurotransmitter systems are distributed throughout the brain and sub-serve many functions in addition to sleep, the precise circuit mechanisms by which these neurotransmitters regulate …

Effects Of Sleep-Deprivation On Decision-Making And Action Selection, Shalin N. Shah

Undergraduate Honors Theses

This thesis addresses neuroscience research focusing on the brain’s mechanisms underlying behavioral choice, or prioritization, and decision-making. The research has been conducted with Drosophila melanogaster, the fruit fly – a good model from both the behavioral and neural perspectives. This project specifically observes the co-regulation of sleep with two other behaviors – courtship and oviposition. The overlap between the sleep and courtship circuits in the brain should provide a good model for behavioral prioritization, and the interaction between sleep and ovipositional preference should provide a model for understanding the effects of sleep on decision-making. All three of these adaptive behaviors …

Changes In Synaptic Protein Content And Signaling In A Mouse Model Of Fragile X Syndrome, Kelly Birch, Peter W. Vanderklish Phd

Undergraduate Honors Theses

Fragile X Syndrome--the most common inherited form of intellectual disability--is characterized by low IQ, impaired social interaction, hyperactivity and impulsivity, and abnormal physical traits including an elongated face and protruding ears. Nearly half of all children with Fragile X also meet diagnostic criteria for autism spectrum disorder. Fragile X is caused by a trinucleotide repeat expansion on the X chromosome, leading to silencing of the Fragile X mental retardation gene (FMR1) and thus lack of expression of Fragile X mental retardation protein (FMRP). As a key translational suppressor, FMRP is crucial for normal neural development and synaptic function. The current …

Temporal And Spatial Patterns Of Barnacle Settlement Within The Southern, Ca Rocky Intertidal, Diana Fontaine

Undergraduate Honors Theses

Barnacles act as model species for understanding how larval transport processes influence settlement and adult population dynamics. Settlement of barnacle larvae was quantified in the Southern California intertidal from April 2014 through January 2015 and from April through December 2015. Settlement plates (PVC, ~1.9 cm²) were deployed daily at 12-14 locations within our study site in the Bird Rock, La Jolla, California intertidal. Time series of temperature and significant wave height was also collected within the study site. We compared temporal patterns in settlement with changes in temperature and significant wave height. In general, settlement was higher in …

Tropical Trees As Islands: Diversity Accumulation Of Armored Scale Insects (Hemiptera: Diaspididae) On Trees As A Function Of Forest Age, Hannah Shapiro

Undergraduate Honors Theses

Armored scale insects (Hemiptera: Diaspididae) are some of the most invasive insects in the world. These cryptic plant parasites are most often encountered in managed agricultural ecosystems, but very little is known about their distribution, abundance, and diversity in tropical rainforest canopies, where they are likely to have their highest diversity. Because these ubiquitous insects are extreme generalists with undirected dispersal, their diversity (alpha and beta) accumulation can conceivably be modeled according to tenets derived from island biogeography theory. For example, one expectation is that older established trees should boast a higher species diversity and abundance than younger ones. Other …

The Suitability Of Habitats And The Effects Of Human Activities In Osupuko And Olepolos Wildlife Sanctuaries On Maasai Giraffes, Sydney P. Davis

Undergraduate Honors Theses

Habitat quality and resource availability within wildlife dispersal areas in the Amboseli ecosystem are experiencing degradation due to pastoralism and agriculture by humans, which negatively affects the wildlife species that utilize these dispersal areas. Maasai giraffes are a common species that utilize these areas, but information on how human activities and the presence of domestic livestock affects the Maasai giraffe is limited. This study was conducted in two wildlife sanctuaries: Osupuko and Olepolos. Habitat condition assessment was done to determine the quality of habitats found within each sanctuary. The Point-Centered Quadrat Method was used to determine the number of five …

The Effects Of Sustained, High-Velocity Exercise On Gene Expression In California Yellowtail (Seriola Lalandi), Kelli Hatter

Undergraduate Honors Theses

California Yellowtail muscle fibers have been observed to exhibit two drastically different development patterns resulting from the speeds at which they are exercised. When fish are exercised at a moderate rate their epaxial fast-twitch muscle fibers grow in diameter—hypertrophy; when they are exercised at a fast speed, more new epaxial fast-twitch muscle fibers are produced—hyperplasia. To determine the underlying reason for this difference in muscle development, my summer research project and honors thesis exercised fish at: fast, moderate, and control speeds for a sustained amount of time to determine what is happening on a cellular level to cause the observed …

Local Patterns In Host-Selection By Anemone Symbionts In Bocas Del Toro, Panama, Samantha Mercer

Undergraduate Honors Theses

The associations made between many symbiotic cleaner shrimps and their host anemone species are influenced by local ecological factors, resulting in regional variations in symbiont-host preferences. These relationships are crucial parts of aquatic ecosystems, and as we face rapid global environmental change, understanding the local patterns of this host specificity will be essential to maintaining healthy marine environments. However, sea anemones, as well as their symbiotic relationships, from the Caribbean coasts of Panama have been poorly studied and are largely under-represented in the current literature. The purpose of this study is to identify the local host-selection patterns, specifically regarding host-size …

Distribution And Identification Of Fish Eggs In An Internal Wave Transport Mechanism, Claire Kuelbs

Undergraduate Honors Theses

Internal waves have been proven to transport invertebrate larvae onshore, but there has been little indication on whether internal waves transport fish eggs. Fish eggs are typically buoyant and are often found in neustonic samples, and internal waves often cause fronts that transport oils and other light particles. This research aims to determine whether there are patterns to the distribution of fish eggs. One possibility is that offshore fish eggs can be transported onshore, to nearshore nursery habitats. Before 2003, when genetic barcoding was proposed as an identification mechanism, fish eggs could only be identified visually, using color, size, and …