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The Effects Of Photoperiod And Melatonin Injections On The Reproductive System Of Pinealectomized Male Mice Mus Musculus, Icr Strain, John Earnest Constantine
The Effects Of Photoperiod And Melatonin Injections On The Reproductive System Of Pinealectomized Male Mice Mus Musculus, Icr Strain, John Earnest Constantine
Master's Theses
One hundred two male mice , Mus musculus, ICR strain, age four weeks, were obtained. Fifty-one mice were pinealectomized and 51 were sham operated. The animals were divided into three photoperiod groups: 1.5L:22.5D, 14L:10D, 24L; 0D. The mice were subcutaneously injected daily with 10 ug melatonin or control solution from post-operative day J to post-operative day 60, On post-operative day 60 representatives of each photo period-surgery-injection regimen were paired with females. The remaining animals were killed and several organs were removed and weighed, Melatonin injections were progonadal in pinealectomized mice and inhibitory in sham mice in several instances. Histological examination …