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Neurocognitive Markers Of Cognitive Control In Schizophrenia And Functional Outcomes, Sephira Ryman
Neurocognitive Markers Of Cognitive Control In Schizophrenia And Functional Outcomes, Sephira Ryman
Psychology ETDs
Impaired cognitive function results in decreased objective quality of life and community functioning in schizophrenia, resulting in the largest indirect costs from the disease. Disrupted proactive cognitive control, a form of early selection and active goal maintenance, is hypothesized to underlie the broad cognitive deficits observed in patients with schizophrenia. The current study utilized novel electrophysiological (EEG) analytic approach to examine proactive and reactive cognitive control deficits in schizophrenia patients. Behavioral results highlight that patients exhibited a general reduction in reaction time across two multisensory cognitive control tasks, with selective deficits on proactive conditions relative to reactive conditions. The relative …
Moderate Prenatal Alcohol Exposure Impairs Performance In An Object-Place-Paired-Associate Task, Lilliana May Sanchez
Moderate Prenatal Alcohol Exposure Impairs Performance In An Object-Place-Paired-Associate Task, Lilliana May Sanchez
Psychology ETDs
Memory impairments, including spatial and object processing, are often observed in individuals with Fetal Alcohol Spectrum Disorder. Much attention has been directed towards the hippocampus, which displays significant alterations after moderate prenatal alcohol exposure (PAE). In the present study, we tested a moderate PAE rat model in an object-place-paired-associate (OPPA) task, previously shown to require hippocampal processing. The OPPA task was composed of training rats to discriminate between an identical pair of objects presented in 180° opposite arms of a radial arm maze. Animals were given a total of 10 trials per day over 14 consecutive days of training and …