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Full-Text Articles in Life Sciences
Integration Of The Metabolome And Transcriptome Reveals The Metabolites And Genes Related To Nutritional And Medicinal Value In Coriandrum Sativum, Wu Tong, Feng Shu-Yan, Yang Qi-Hang, Preetida J. Bhetariya, Gong Ke, Cui Chun-Lin, Song Jie, Ping Xiao-Rui, Pei Qiao-Ying, Yu Tong, Song Xiao-Ming
Integration Of The Metabolome And Transcriptome Reveals The Metabolites And Genes Related To Nutritional And Medicinal Value In Coriandrum Sativum, Wu Tong, Feng Shu-Yan, Yang Qi-Hang, Preetida J. Bhetariya, Gong Ke, Cui Chun-Lin, Song Jie, Ping Xiao-Rui, Pei Qiao-Ying, Yu Tong, Song Xiao-Ming
Department of Food Science and Technology: Faculty Publications
Coriandrum sativum (Coriander) or Chinese parsley is a culinary herb with multiple medicinal effects, which is widely used in cooking and traditional medicine. It is enriched with essential oils and anti-oxidant compounds with unknown significance. To explore the untapped reservoir of Coriander, we studied the transcriptome and metabolic profiles from three developmental stages. Here, we identified 10 tyrosine metabolic pathway-related genes (TMPRGs), six porphyrins and chlorophyll metabolic pathway-related genes (PCMPRGs), and five Vitamin E metabolic pathway-related genes (VEMPRGs). These genes were associated with the early development of Coriander. Our analysis suggests that these pathways …
Desiccation Tolerance In Streptophyte Algae And The Algae To Land Plant Transition: Evolution Of Lea And Mip Protein Families Within The Viridiplantae, Burkhard Becker, Xuehuan Feng, Yanbin Yin, Andreas Holzinger
Desiccation Tolerance In Streptophyte Algae And The Algae To Land Plant Transition: Evolution Of Lea And Mip Protein Families Within The Viridiplantae, Burkhard Becker, Xuehuan Feng, Yanbin Yin, Andreas Holzinger
Department of Food Science and Technology: Faculty Publications
The present review summarizes the effects of desiccation in streptophyte green algae, as numerous experimental studies have been performed over the past decade particularly in the early branching streptophyte Klebsormidium sp. and the late branching Zygnema circumcarinatum. The latter genus gives its name to the Zygenmatophyceae, the sister group to land plants. For both organisms, transcriptomic investigations of desiccation stress are available, and illustrate a high variability in the stress response depending on the conditions and the strains used. However, overall, the responses of both organisms to desiccation stress are very similar to that of land plants. We highlight the …
In Silico And Ex Vivo Approaches Identify A Role For Toll-Like Receptor 4 In Colorectal Cancer, Daniel A. Sussman, Rebeca Santoalalla, Pablo A. Bejarano, Monica T. Garcia-Buitrago, Maria T. Perez, Maria T. Abreu, Jennifer L. Clarke
In Silico And Ex Vivo Approaches Identify A Role For Toll-Like Receptor 4 In Colorectal Cancer, Daniel A. Sussman, Rebeca Santoalalla, Pablo A. Bejarano, Monica T. Garcia-Buitrago, Maria T. Perez, Maria T. Abreu, Jennifer L. Clarke
Department of Food Science and Technology: Faculty Publications
Background: Inflammation increases the risk of colorectal cancer (CRC). We and others have described a role for TLR4, the receptor for LPS, in colon cancer. To explore the relationships between TLR4 expression and CRC, we combined the strength of transcriptome array data and immunohistochemical (IHC) staining. Methods: TLR4 signal intensity was scored in the stromal and epithelial compartments. Detection of differential expression between conditions of interest was performed using linear models, Cox proportional hazards models, and empirical Bayes methods. Results: A strong association between TLR4 expression and survival was noted, though a dichotomous relationship between survival and specific TLR4 transcripts …