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Full-Text Articles in Life Sciences

How Does A Mycobacterium Change Its Spots? Applying Molecular Tools To Track Diverse Strains Of Mycobacterium Avium Subspecies Paratuberculosis, John Bannantine, L.-L. Li, Srinand Sreevatsan, Vivek Kapur Jan 2013

How Does A Mycobacterium Change Its Spots? Applying Molecular Tools To Track Diverse Strains Of Mycobacterium Avium Subspecies Paratuberculosis, John Bannantine, L.-L. Li, Srinand Sreevatsan, Vivek Kapur

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Defining genetic diversity in the wake of the release of several Mycobacterium avium subsp. paratuberculosis (MAP) genome sequences has become a major emphasis in the molecular biology and epidemiology of Johne’s disease research. These data can now be used to define the extent of strain diversity on the farm. However, to perform these important tasks, researchers must have a way to distinguish the many MAP isolates/strains that are present in the environment or host to enable tracking over time. Recent studies have described genetic diversity of the Mycobacterium avium complex (MAC), of which MAP is a member, through pulsed-field gel …


Feral Swine Brucellosis In The United States And Prospective Genomic Techniques For Disease Epidemiology, Owen P. Leiser, Joseph L. Corn, Brandon S. Schmit, Paul S. Keim, Jeffrey T. Foster Jan 2013

Feral Swine Brucellosis In The United States And Prospective Genomic Techniques For Disease Epidemiology, Owen P. Leiser, Joseph L. Corn, Brandon S. Schmit, Paul S. Keim, Jeffrey T. Foster

USDA Wildlife Services: Staff Publications

Brucellosis is a common infection of feral swine throughout the United States. With the recent expansion of feral swine populations across the country, this disease poses an increasing threat to agriculture and hunters. The standard approach to Brucella surveillance in feral swine has been serological testing, which gives an indication of past exposure and is a rapid method of determining populations where Brucella is present. More in-depth analyses require bacterial isolation to determine the Brucella species and biovar involved. Ultimately, for a comprehensive understanding of Brucella epizootiology in feral swine, incorporation of genotyping assays has become essential. Fortunately, the past …


Ecology Of Zoonotic Infectious Diseases In Bats: Current Knowledge And Future Directions, D. T. S. Hayman, R. A. Bowen, P. M. Cryan, G. M. Mccracken, T. J. O'Shea, A. J. Peel, A. T. Gilbert, C. T. Webb, J. L. N. Wood Jan 2013

Ecology Of Zoonotic Infectious Diseases In Bats: Current Knowledge And Future Directions, D. T. S. Hayman, R. A. Bowen, P. M. Cryan, G. M. Mccracken, T. J. O'Shea, A. J. Peel, A. T. Gilbert, C. T. Webb, J. L. N. Wood

USDA Wildlife Services: Staff Publications

Bats are hosts to a range of zoonotic and potentially zoonotic pathogens. Human activities that increase exposure to bats will likely increase the opportunity for infections to spill over in the future. Ecological drivers of pathogen spillover and emergence in novel hosts, including humans, involve a complex mixture of processes, and understanding these complexities may aid in predicting spillover. In particular, only once the pathogen and host ecologies are known can the impacts of anthropogenic changes be fully appreciated. Cross-disciplinary approaches are required to understand how host and pathogen ecology interact. Bats differ from other sylvatic disease reservoirs because of …