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Full-Text Articles in Life Sciences
Evaluation Of Berry Extracts On Intestinal Digestive Enzymes And Sugar Transporters, Jungbae Ohrenberger
Evaluation Of Berry Extracts On Intestinal Digestive Enzymes And Sugar Transporters, Jungbae Ohrenberger
Masters Theses
T2DM is a chronic disease characterized by postprandial hyperglycemia. One of the therapeutic approaches to attenuate hyperglycemia is to inhibit intestinal ɑ-glucosidase enzyme and/or suppress glucose transporters that regulate intestinal glucose transporters such as SGLT1 & GLUT2. Berries rich in polyphenol antioxidants have various health benefits. Although the antidiabetic effects of various berry extracts or berry mixture in pre-clinical and clinical studies, the underlying pathways at the molecular level is still unclear. In this study, we investigated antioxidant and antidiabetic effects of selected berry extracts by determining free radical scavenging activates, Caco-2 intestinal ɑ-glucosidase activity, glucose uptake and the gene …
Interfacing Continuous Measurement Of Glucose And Physical Activity To Predict Glycemic Control In Individuals With Type 2 Diabetes, Jennifer Blankenship
Interfacing Continuous Measurement Of Glucose And Physical Activity To Predict Glycemic Control In Individuals With Type 2 Diabetes, Jennifer Blankenship
Doctoral Dissertations
Physical activity is a cornerstone in the management of hyperglycemia and risk of cardiovascular disease in type 2 diabetes (T2D). However, the dose response relationship between physical activity and glucose regulation is not well defined. The overall goal of this dissertation was to assess the magnitude and timing of changes of daily glucose concentrations in response to continuous and intermittent light physical activity in T2D. Through utilizing continuous glucose monitors (CGM) and physical activity monitoring concurrently, we were able to assess the glycemic impact of physical activity and sedentary behavior in the free-living environment. Study 1 aimed to examine the …