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- Allelic Discrimination Real-Time PCR (1)
- Cellular immune responses (1)
- Consensus sequence (1)
- Equine Herpesvirus Type-1 (1)
- Equine infectious anemia virus (1)
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- Immunodominant recognition (1)
- Immunodominant shifting (1)
- Immunogen (1)
- Murine Model (1)
- Neuropathogenic EHV-1 (1)
- Non-Neuropathogenic EHV-1 (1)
- ORF30 Real-Time PCR (1)
- RacH (1)
- Serum antibody response (1)
- Streptococcus equi subsp. equi (1)
- Streptococcus equi subsp. zooepidemicus (1)
- Vaccine vector (1)
Articles 1 - 3 of 3
Full-Text Articles in Life Sciences
Equine Serum Antibody Responses To Streptococcus Equi And Streptococcus Zooepidemicus, Rafaela De Negri
Equine Serum Antibody Responses To Streptococcus Equi And Streptococcus Zooepidemicus, Rafaela De Negri
Theses and Dissertations--Veterinary Science
Streptococcus zooepidemicus (Sz) and Streptococcus equi (Se) share 98% DNA sequence homology, but display different pathogenic properties. Infection by one organism does not cross-protect against the other. To better understand pathogenic differences between these organisms and gain information about which proteins are expressed in horses infected experimentally with Se, intrauterine Sz or naturally with respiratory Sz we compared antibody specificities of convalescent sera using ELISA. These comparisons were based on sets of 8 and 14 immunoreactive recombinant proteins of Se strain CF32 and Sz strain NC78, respectively. Sera from donkeys that were previously naturally affected with strangles and later developed …
Development Of A New Allelic Discrimination Real-Time Pcr Assay For The Diagnosis Of Equine Herpesvirus-1 And Characterization Of The Virulence Determinants Of The Virus, Kathryn L. Smith
Theses and Dissertations--Veterinary Science
Equine herpesvirus-1 (EHV-1) can cause acute upper respiratory tract disease, abortion, neonatal death and neurological disease in horses. Rapid, accurate and timely diagnosis of EHV-1 infection in horses is important to curtail the spread of this pathogen. It has been reported that the neuropathogenic phenotype of EHV-1 can result from a single non-synonymous nucleotide substitution at position 2254 (A→G2254) in open reading frame 30 (ORF30). This was the basis for the development of an allelic discrimination, real-time PCR assay to distinguish between potential neuropathogenic and non-neuropathogenic EHV-1 strains. However, PCR analysis of a panel of EHV-1 abortion isolates …
Evidence For The Maturation Of Cellular Immune Responses In Equine Infectious Anemia Virus-Infected Ponies, Chong Liu
Theses and Dissertations--Veterinary Science
Equine infectious anemia virus (EIAV) has been used as a model to investigate protective mechanisms against lentiviruses. Unlike other lentiviruses, EIAV replication can be eventually controlled in most infected horses leading to an inapparent carrier state free of overt clinical signs which can last for many years. Maintenance of this carrier state is absolutely dependent on active immune responses as evidenced by the fact that immunosuppressive drugs can induce the recurrence of disease. However, the immune mechanisms that are responsible for this control of infection are not yet identified. As the resolution of the initial infection is correlated with the …