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Full-Text Articles in Life Sciences
Genetic Analysis Of The Endangered Gray Bat Species (Myotis Grisescens), Emma Fitzgerald
Genetic Analysis Of The Endangered Gray Bat Species (Myotis Grisescens), Emma Fitzgerald
Lewis Honors College Capstone Collection
This study attempts to analyze the genetics using specific haplotype sequences of the endangered gray bat to determine genetic events that have happened in the past as well as determining how the species population has changed over time. We were able to conduct a Tajima’s D test to investigate whether a potential bottleneck has occurred. A linear regression of the genetic vs. geographical distance was produced to investigate the patterns of haplotype distribution. The species past distribution was compared to the current distribution using known collected specimens. A map of future predictions was constructed using present and future climate layers …
The Role Of Rapgap1 In Sxl Activation In Drosophila Melanogaster, Katherine M. Barnes
The Role Of Rapgap1 In Sxl Activation In Drosophila Melanogaster, Katherine M. Barnes
Lewis Honors College Capstone Collection
The master switch of the sexual differentiation and dosage compensation pathway in Drosophila is the sex lethal gene, Sxl. The early promoter, SxlPe, is activated in females, resulting in female-specific splicing of later transcripts (notably the late Sxl transcript SxlPm), while inactive in males. Chromatin immunoprecipitation (ChIP) assays have previously shown association of two conventionally heterochromatin-localized proteins, HOAP and HP1, at SxlPe, and in situ hybridization as well as RT-PCR assays have confirmed a repressive role for HOAP and both repressive and activating roles for HP1. The mechanism for the activity shift of HP1 is currently unknown. Deletions in the …