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Full-Text Articles in Life Sciences

Cycads, Flying Foxes, And Brain Disease In Humans, Logan Disney Jan 2018

Cycads, Flying Foxes, And Brain Disease In Humans, Logan Disney

Lewis Honors College Capstone Collection

Cycads are a group of ancient gymnosperms with a rich fossil history. While they once dominated the world’s forests, their adaptation to warm climates has now restricted them to tropical areas. They are not widely eaten by humans due to their known toxicity, but some indigenous groups of the Pacific Islands, such as the Chamorro people of Guam, have developed methods of washing the seeds for safe consumption. Cycad seeds are a common dietary item of several mammals. One such mammal, the flying fox, is considered a delicacy to several indigenous groups. In the mid-twentieth century, these groups also expressed …


Functional Analysis Of Protease Adamts 6 During Vertebrate Eye Formation, Austin Taylor Jan 2018

Functional Analysis Of Protease Adamts 6 During Vertebrate Eye Formation, Austin Taylor

Lewis Honors College Capstone Collection

Extracellular matrix (ECM) remodeling and epithelial sheet fusion occur during the development of many different tissues, including the vertebrate eye (Lu et al., 2011) (Pai et al., 2012). During morphogenesis of the eye, the ventral hemisphere of the developing retinal tissue forms an opening called the optic fissure which must undergo epithelial fusion (Pai et al., 2012). Failure of optic fissure fusion leads to a congenital blinding disorder called coloboma (Gregory-Evans, 2004). A long standing question pertaining to the mechanism of optic fissure fusion is exactly which ECM remodeling enzymes are actively involved in dismantling the ECM to allow for …