Life Sciences Commons^™

Investigation Of The Genetic Interactions Between Hippo Signaling Pathway And Drosophila C-Terminal Src Kinase (Dcsk), Hailey Jimin Kwon

Honors Theses

The focus of my research revolved around the intersection between the Hippo tumor suppressor pathway and the Src oncogenic pathway. Both pathways control tissue and organ size during development by regulating cell proliferation, cell death, cell migration, and cell adhesion. Aberrant functions in either pathway are often detected in human cancers and correlate with poor prognosis. The Drosophila C-terminal Src kinase (dCsk) is a genetic modifier of warts (wts), a tumor-suppressor gene in the Hippo pathway, and interacts with the Src oncogene. Reduction in dCsk expression and the consequent activation of Src are reported in hepatocellular and colorectal tumors. …

Coding Dna Into Music: An Alternate Way Of Analysis, Samuel Fesenmeier

Honors Theses

In the study, we are analyzing the human genome in order to determine patterns that may tell something about how DNA functions. Patterns require an explanation: it is highly improbable that they are random occurrence. These patterns may hint to something about how DNA functions. There are known patterns already discovered in DNA. For example, in the coding portion, three base pairs translate to a specific amino acid. In the non coding portion, however, specific patterns are not as simple.

We will search for patterns by applying a coding system that turns DNA into music. Music may serve as a …