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The Effects Of Maternal Diet During Gestation On Postnatal Growth Of Lambs And On Metabolic Hormones In Lambs And Ewes, Amanda R. Fox
The Effects Of Maternal Diet During Gestation On Postnatal Growth Of Lambs And On Metabolic Hormones In Lambs And Ewes, Amanda R. Fox
Honors Scholar Theses
Fetal programming is defined as when a stimulus at a vital stage of development results in permanent effects that persist throughout the lifetime of the individual (Lucas, 1991). There is evidence that poor maternal diet, consisting of both undernutrition and overnutrition, during gestation has permanent negative effects on the growth and development of offspring through fetal programming. Fetal programming enhances the ability of the fetus to absorb and use nutrients while in-utero, ensuring postpartum survival (Hales and Barker, 1992). However, in a postnatal environment where nutrition is plentiful, fetal programming results in negative health consequences (Wu et al., 2006). We …
Effects Of Poor Maternal Nutrition On Gh, Igf-I, Igfbp-2 And -3, Insulin, And Leptin Concentrations In Pregnant Ewes, Michelle E. Forella
Effects Of Poor Maternal Nutrition On Gh, Igf-I, Igfbp-2 And -3, Insulin, And Leptin Concentrations In Pregnant Ewes, Michelle E. Forella
Honors Scholar Theses
Maternal hormones impact fetal growth and development through their effect on nutrient partitioning and placental development. Maternal diet is one factor regulating maternal hormone concentrations. We hypothesized that during gestation, diet alters concentrations of maternal metabolic hormones. Pregnant ewes (n=36; 12/treatment) were individually fed 1 of 3 diets [100% (CON), 140% (OVER), or 60% (RES) NRC requirements] from wk 5 of gestation until parturition. Weekly blood samples (20 mL) were obtained via jugular venipuncture and BW was measured. Concentrations of GH, IGF-I and leptin were determined by RIA. Insulin was determined by ELISA. Data were analyzed using ANOVA. By the …