Life Sciences Commons^™

Dynamic Variability Of Isometric Action Tremor In Precision Pinching, Tim Eakin, Waneen Spirduso, Karen Francis

Kinesiology (Formerly Exercise and Sport Science)

Evolutionary development of isometric force impulse frequencies, power, and the directional concordance of changes in oscillatory tremor during performance of a two-digit force regulation task was examined. Analyses compared a patient group having tremor confounding volitional force regulation with a control group having no neuropathological diagnosis. Dependent variables for tremor varied temporally and spatially, both within individual trials and across trials, across individuals, across groups, and between digits. Particularly striking findings were magnitude increases during approaches to cue markers and shifts in the concordance phase from pinching toward rigid sway patterns as the magnitude increased. Magnitudes were significantly different among …

Neurotechnology And Psychiatric Biomarkers, William Bosl

Nursing and Health Professions Faculty Research and Publications

No abstract provided.

Parenting As Phenotype: A Behavioral Genetic Approach To Understanding Parenting, Shirley Mcguire, Nancy Segal, S. Hershberger

Psychology

This article discusses the behavioral genetic (BG) approach to parenting. Parenting is considered a phenotype that can be influenced by nature and nurture. Genetic contributions to parenting are conceptualized as evidence of genotype–environment correlation (rGE). Early BG studies focused on demonstrating that some parenting dimensions were heritable due to passive and evocative rGE processes. Current studies are investigating moderators and mediators of genetic and environmental contributions to parenting. The paper uses parent and child report data on parental warmth from the Twins, Adoptees, Peers, and Siblings study to illustrate the BG approach. Results show that heritability is …

Direct Fitness Correlates And Thermal Consequences Of Facultative Aggregation In A Desert Lizard, Alison R. Davis Rabosky, Ammon Corl, Heather E.M. Liwanag, Yann Surget-Groba, Barry Sinervo

Biology Faculty Publications

Social aggregation is a common behavioral phenomenon thought to evolve through adaptive benefits to group living. Comparing fitness differences between aggregated and solitary individuals in nature – necessary to infer an evolutionary benefit to living in groups – has proven difficult because communally-living species tend to be obligately social and behaviorally complex. However, these differences and the mechanisms driving them are critical to understanding how solitary individuals transition to group living, as well as how and why nascent social systems change over time. Here we demonstrate that facultative aggregation in a reptile (the Desert Night Lizard, Xantusia vigilis) confers …

Receptor Chimeras Demonstrate That The C-Terminal Domain Of The Human Cytomegalovirus Us27 Gene Product Is Necessary And Sufficient For Intracellular Receptor Localization, Lance K. Stapleton, Kathleen L. Arnolds, Angela P. Lares, Tori M. Devito, Juliet V. Spencer

Biology Faculty Publications

Background

Human cytomegalovirus (HCMV) is ubiquitous in the population but generally causes only mild or asymptomatic infection except in immune suppressed individuals. HCMV employs numerous strategies for manipulating infected cells, including mimicry of G-protein coupled receptors (GPCRs). The HCMV US27 gene product is a putative GPCR, yet no ligand or signaling has been identified for this receptor. In the present study, immunofluorescence microscopy was used to examine the cellular distribution of wild type US27, as well as US27 deletion mutants and chimeric receptors.

Results

In transiently transfected cells, wild type US27 was found primarily in intracellular compartments, in striking contrast …