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The University of Maine

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2017

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Microglial Activation Immediately After Ethanol Withdrawal And 1 Week After Ethanol Withdrawal In Female C3h Mice, Sarah Holbrook May 2017

Microglial Activation Immediately After Ethanol Withdrawal And 1 Week After Ethanol Withdrawal In Female C3h Mice, Sarah Holbrook

Honors College

Alcohol abuse is the fourth leading cause of preventable death in the United States (National Institute on Alcohol Abuse and Alcoholism [NIAAA], 2016). Alcohol affects us on a molecular, biological, and even societal level. Liver damage, cancer, and drunk driving accidents are only a few adverse consequences of alcohol abuse. Studies have also shown that alcohol abuse can damage the brain, in part by activating the central nervous system’s immune system, leading to inflammation and demyelination. This damage may lead to alcohol-related psychiatric disorders, motor impairment, and cognitive disabilities. Studies have also shown that females tend to exhibit more damage …