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Full-Text Articles in Life Sciences

The Cardiovascular Response To Acute Hypoxic Conditions In Danio Rerio, Bryce Fetterman Jan 2020

The Cardiovascular Response To Acute Hypoxic Conditions In Danio Rerio, Bryce Fetterman

Williams Honors College, Honors Research Projects

There are many fish that can withstand hypoxia levels. One in particular is the zebrafish (Danio rerio). The zebrafish is a small-sized, Cyprinid teleost fish, and has been used in a laboratory setting for many reasons. A few reasons being that they are widely available, easy to care for, and the cost for these fish are very low. There are various reasons why these fish are used as a model. One main reason is because their cardiovascular system is one of the first developing organs. This allows for better resolution when studying the cardiovascular system. The purpose of …


The Effects Of Methamphetamine Exposure On Cardiovascular Development In Combination With Hypoxia In Danio Rerio, Sarah Donaldson Jan 2017

The Effects Of Methamphetamine Exposure On Cardiovascular Development In Combination With Hypoxia In Danio Rerio, Sarah Donaldson

Williams Honors College, Honors Research Projects

The purpose of this study was to determine the effects of methamphetamine combined with hypoxia on the development and function of the cardiovascular system in Danio rerio embryos. It was hypothesized that the combined effect of the drug and decreased oxygen concentration would result in decreased cardiac parameters due to underdevelopment of the ventricle and vessels resulting from cardiomyopathy and lack of blood flow to tissues. It was found that methamphetamine exposure correlated to an increase in stroke volume, caudal artery and vein diameters and RBC velocities alone, while having a multiplicative effect of increasing arterial RBC velocity when combined …


Grazing And Virus-Induced Mortality Of Microbial Populations Before And During The Onset Of Annual Hypoxia In Lake Erie, Christopher J. Gobler, Timothy W. Davis, Sarah N. Deonarine, Matthew A. Saxton, Peter J. Lavrentyev, Frank J. Jochem May 2008

Grazing And Virus-Induced Mortality Of Microbial Populations Before And During The Onset Of Annual Hypoxia In Lake Erie, Christopher J. Gobler, Timothy W. Davis, Sarah N. Deonarine, Matthew A. Saxton, Peter J. Lavrentyev, Frank J. Jochem

Biology Faculty Research

Lake Erie is the most productive of the North American Great Lakes and experiences annual periods of hypolimnetic hypoxia with unknown consequences for the microbial food web. We established the abundances and mortality rates of microbes in Lake Erie during thermal stratification and determined how they varied with changes in bottom-water dissolved oxygen concentrations. The microbial plankton community (heterotrophic bacteria, Cyanobacteria, eukaryotic phytoplankton, nanozooplankton, microzooplankton) was quantified in surface and bottom waters along with measurements of herbivory and bacterivory rates on eukaryotic and prokaryotic picoplankton and rates of viral lysis of bacteria. High rates of grazing mortality of prokaryotic picoplankton …