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- Bacteria (1)
- Biosensor (1)
- Brucellosis (1)
- Metalloporphyrins · Electrospinning · Nanofiber · Green oxidative degradation · Crystal violet (1)
- Nanofibers Electrospinning Wound healing Wound dressing Tamarindus indica PMMA PEO Cellulose acetate Antimicrobial (1)
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- PVA-Aloe vera hydrogel membranes · Caffeine · Vitamin C · Physical crosslinking · In-vitro caffeine release · In-vivo study (1)
- Polyvinyl alcohol- hyaluronic acid- cellulose nanocrystals (PVA/HA/CNCs) · Hydrogel membranes · Solution casting crosslinking · Freeze-thawing crosslinking (1)
- Surface plasmon spectroscopy (1)
- Tissue engineering and regenerative medicine; biopolymers; nanofabrication techniques; additive manufacturing; rapid prototyping; customized therapy 3D scaffolds (1)
Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Electrospun Tamarindus Indica-Loaded Antimicrobial Pmma/Cellulose Acetate/Peo Nanofibrous Scaffolds For Accelerated Wound Healing: In-Vitro And In-Vivo Assessments, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Electrospun Tamarindus Indica-Loaded Antimicrobial Pmma/Cellulose Acetate/Peo Nanofibrous Scaffolds For Accelerated Wound Healing: In-Vitro And In-Vivo Assessments, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Nanotechnology Research Centre
In this work, Tamarindus indica (T. indica)-loaded crosslinked poly(methyl methacrylate) (PMMA)/cellulose acetate (CA)/poly(ethylene oxide) (PEO) electrospun nanofibers were designed and fabricated for wound healing applications. T. indica is a plant extract that possesses antidiabetic, antimicrobial, antioxidant, antimalarial and wound healing properties. T. indica leaves extract of different concentrations were blended with a tuned composition of a matrix comprised of PMMA (10 %), CA (2 %) and PEO (1.5 %), and were electrospun to form smooth, dense and continuous nanofibers as illustrated by SEM investigation. In vitro evaluation of T. indicaloaded nanofibers on normal human skin fibroblasts (HBF4) revealed a high …
Synthesis And In‑Vitro Anti‑Proliferative With Antimicrobial Activity Of New Coumarin Containing Heterocycles Hybrids, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Synthesis And In‑Vitro Anti‑Proliferative With Antimicrobial Activity Of New Coumarin Containing Heterocycles Hybrids, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Nanotechnology Research Centre
series of new coumarin-N-heterocyclic hybrids, coumarin-quinolines 7a–e, coumarin-acridines 10b,c and coumarin-neocryptolepines 13b,c were synthesized and evaluated for their anticancer and antimicrobial activities. The structures of all synthesized hybrids were confirmed by FT-IR, 1HNMR, 13C-NMR, and MS spectrometry. The anti-proliferative activity of hybrids 7a–e, 10c and 13c were bio-evaluated using MTT-assay against colon (CaCo-2), lung (A549), breast (MDA-MB-231), and hepatocellular carcinoma (HepG-2) human cancer cell lines using doxorubicin as a reference drug. The results demonstrated that, all hybrids displayed moderate to good anti-proliferative activity against the cell lines. The most active hybrids were 7a–d and 10c against CaCo-2 cancer cell line …
Physically And Chemically‑Crosslinked L‑Arginine‑Loaded Polyvinyl Alcohol‑ Hyaluronic Acid‑ Cellulose Nanocrystals Hydrogel Membranes For Wound Healing: Influence Of Crosslinking Methods On Biological Performance Of Membranes In‑Vitro, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Physically And Chemically‑Crosslinked L‑Arginine‑Loaded Polyvinyl Alcohol‑ Hyaluronic Acid‑ Cellulose Nanocrystals Hydrogel Membranes For Wound Healing: Influence Of Crosslinking Methods On Biological Performance Of Membranes In‑Vitro, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Nanotechnology Research Centre
Two types of polyvinyl alcohol-blended hyaluronic acid and cellulose nanocrystals (PVA/HA/CNCs) hydrogels membranes were developed as delivery agents for L-arginine using chemical/and/physical crosslinking methods for exploring biological performance of the obtained membranes. Chemically and physically/crosslinked membranes were fabricated by solution-casting and freeze-thawing techniques, respectively. The characterization of the crosslinked PVA/HA/CNCs/Larginine membranes were conducted by SEM, FTIR, TGA, swelling ratio, and in—vitro L-arginine release. Furthermore, applying two types of crosslinked membranes in vitro were investigated in terms of cytotoxicity, hemocompatibility, and cell adhesion affinity of HFB-4 cell line. Chemical and physical-crosslinked membranes were verified through the esterification and hydrogen bonds interactions, …
Catalytic Activity Of Co (Ii)‑Porphyrin Anchored Onto Polymeric Support Of Electrospun Polyacrylonitrile Nanofiber: Synthesis And Efficient Green Oxidation Of Crystal Violet Dye With Hydrogen Peroxide, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Catalytic Activity Of Co (Ii)‑Porphyrin Anchored Onto Polymeric Support Of Electrospun Polyacrylonitrile Nanofiber: Synthesis And Efficient Green Oxidation Of Crystal Violet Dye With Hydrogen Peroxide, Elbadawy A. Kamoun, Elbadawy A. Kamoun
Nanotechnology Research Centre
novel method was explored in this study to address water contamination challenges by utilizing nanofiber mat-supported metalloporphyrin materials. Specifically, electrospinning was employed to create various compositions of polyacrylonitrile (PAN) mixed with different concentrations of Co(II) complex of tetrakis-5, 10, 15, 20 (4-hydroxyphenyl)porphyrin Co(II)TPHPP 1 anchored to chloroacetylated poly (p-hydroxy styrene) CAPS. These resulting nanofiber mat-supported metalloporphyrin materials were comprehensively analyzed using UV, FTIR spectrum, SEM, and TGA thermographs. The study found that the designed nanofibers acted as efficient catalysts for the oxidative breakdown of crystal violet (CV) dye using H2O2 in aqueous solutions. Among these materials, the nanofiber composed of …
Novel Physically‑Crosslinked Caffeine And Vitamin C‑Loaded Pva/ Aloe Vera Hydrogel Membranes For Topical Wound Healing: Synthesis, Characterization And In‑Vivo Wound Healing Tests, Elbadawy Kamoun, Elbadawy A. Kamoun
Novel Physically‑Crosslinked Caffeine And Vitamin C‑Loaded Pva/ Aloe Vera Hydrogel Membranes For Topical Wound Healing: Synthesis, Characterization And In‑Vivo Wound Healing Tests, Elbadawy Kamoun, Elbadawy A. Kamoun
Nanotechnology Research Centre
Novel physically-crosslinked PVA membranes blended with Aloe vera extract were fabricated by solution-casting method. Physically-crosslinking process is depending on the rearrangement of PVA chains forming intermolecular hydrogen bonding with removal of water molecules using propanol as a stabilizing agent. The structure of crosslinked membranes was characterized by FT-IR, SEM, TGA, and XRD analyses and confirmed via gel faction and swelling ratio studies. Caffeine and vitamin C loaded-PVA/Aloe vera membranes were bio-assessed in terms of their impact on the wound healing using Wistar albino rats as an animal model. In vitro evaluation includes protein adsorption showed that the fabricated membranes improved …
A Review Of 3d Polymeric Scaffolds For Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, And Challenges, Hassan Nageh, Ahmed G. Abdelaziz, Sara M. Abdo, Mohga S. Abdalla, Asmaa A. Amer, Abdalla Abdal-Hay, Ahmed Barhoum
A Review Of 3d Polymeric Scaffolds For Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, And Challenges, Hassan Nageh, Ahmed G. Abdelaziz, Sara M. Abdo, Mohga S. Abdalla, Asmaa A. Amer, Abdalla Abdal-Hay, Ahmed Barhoum
Nanotechnology Research Centre
Over the last few years, biopolymers have attracted great interest in tissue engineering and regenerative medicine due to the great diversity of their chemical, mechanical, and physical properties for the fabrication of 3D scaffolds. This review is devoted to recent advances in synthetic and natural polymeric 3D scaffolds for bone tissue engineering (BTE) and regenerative therapies. The review comprehensively discusses the implications of biological macromolecules, structure, and composition of polymeric scaffolds used in BTE. Various approaches to fabricating 3D BTE scaffolds are discussed, including solvent casting and particle leaching, freeze-drying, thermally induced phase separation, gas foaming, electrospinning, and sol–gel techniques. …
Development Of A Novel Highly-Sensitive Brucellosis Sensor Based On Surface Plasmon Resonance Spectroscopy, Amal Kasry, Ihab Adly, Asharf Sayour, Hossam Sayour
Development Of A Novel Highly-Sensitive Brucellosis Sensor Based On Surface Plasmon Resonance Spectroscopy, Amal Kasry, Ihab Adly, Asharf Sayour, Hossam Sayour
Nanotechnology Research Centre
Brucellosis is considered a significant health threat, it is an infectious disease caused by the bacteria Brucella, which can spread from animals to humans causing severe diseases. Through this project, we aim to develop a very highly sensitive biosensor to detect Brucella early before spreading. This sensor is based on surface plasmon resonance (SPR) technique, which is used to analyze kinetics of interaction between biomolecules. It can detect down to picomolar concentrations of some proteins.