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Full-Text Articles in Life Sciences
Lysine Mediation Of Neuroendocrine Food Regulation In Guinea Fowl, Ashley C. Payne, Xiaofei Wang, Michael T. Ivy, A. Stewart, Kiimya Nelson, Carl E. Darris, Samuel N. Nahashon
Lysine Mediation Of Neuroendocrine Food Regulation In Guinea Fowl, Ashley C. Payne, Xiaofei Wang, Michael T. Ivy, A. Stewart, Kiimya Nelson, Carl E. Darris, Samuel N. Nahashon
Biology Faculty Research
In poultry, obesity is partly influenced by food intake, and is increasingly becoming a nationwide problem. Hypothalamic food intake mechanisms are involved metabolically and neurologically via two peptide hormones, leptin and ghrelin, and the amino acid glutamate, which is enzymatically derived from lysine metabolism. We hypothesize that lysine homeostasis mediates regulation of feed intake and performance characteristics via the brain–liver axis through glutamate sensing. The objective was to examine the effects of lysine homeostasis in avian food regulation and performance through neuroendocrine signaling. One-day-old male French Guinea fowl (GF) keets (n = 270) were weighed and randomly assigned to 5 …
Viral Infections And Interferons In The Development Of Obesity, Yun Tian, Jordan Jennings, Yuanying Gong, Yongming Sang
Viral Infections And Interferons In The Development Of Obesity, Yun Tian, Jordan Jennings, Yuanying Gong, Yongming Sang
Agricultural and Environmental Sciences Faculty Research
Obesity is now a prevalent disease worldwide and has a multi-factorial etiology. Several viruses or virus-like agents including members of adenoviridae, herpesviridae, slow virus (prion), and hepatitides, have been associated with obesity; meanwhile obese patients are shown to be more susceptible to viral infections such as during influenza and dengue epidemics. We examined the co-factorial role of viral infections, particularly of the persistent cases, in synergy with high-fat diet in induction of obesity. Antiviral interferons (IFNs), as key immune regulators against viral infections and in autoimmunity, emerge to be a pivotal player in the regulation of adipogenesis. In this review, …