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Articles 1 - 8 of 8
Full-Text Articles in Life Sciences
Development Of Novel Pectinase And Xylanase Juice Clarification Enzymes Via A Combined Biorefinery And Immobilization Approach, Shady Hassan
Development Of Novel Pectinase And Xylanase Juice Clarification Enzymes Via A Combined Biorefinery And Immobilization Approach, Shady Hassan
Doctoral
Hydrolytic enzymes, such as pectinase and xylanase, maybe harnessed for numerous industrial applications in food industry. Therefore, economic factors such as achievement of optimum yieldsandoverall production costs, in addition to biocatalyst instability,are the main obstacles tothe industrial production and exploitation of a enzymes. For example, microbially-derived enzymes are typically produced in fermenters using expensive growth media, which may account for 30 to 40% of the production cost, and such expense may be compounded further by downstream processing operations.To counter such disadvantages, the major trend in industrial utilization of enzymes in cost-sensitive processes has been to immobilize such biocatalysts on a …
Chemical Effects Of Cold Atmospheric Plasma On Food Nutrients, Juan Manuel Pérez Andrés
Chemical Effects Of Cold Atmospheric Plasma On Food Nutrients, Juan Manuel Pérez Andrés
Doctoral
A range of nonthermal techniques have demonstrated process efficacy in ensuring food product safety, extension of shelf-life and in general a retention of key quality attributes. However, various physical, chemical and biochemical effects of nonthermal techniques on both macro and micronutrients are evident, leading to both desirable and undesirable changes in food products. It is important to outline the effects of non-thermal techniques on food chemistry and the associated degradation mechanisms with the treatment of foods. Oxidation is one of the key mechanisms responsible for undesirable effects induced by non-thermal techniques. Degradation of key macromolecules largely depends on the processing …
Bioavailability And Modes Of Action Of Novel Metal Based Phenanthroline Drugs, Tadhg O’Leary
Bioavailability And Modes Of Action Of Novel Metal Based Phenanthroline Drugs, Tadhg O’Leary
Doctoral
Metal-basedcompounds have been utilised as chemotherapeutic agents for the last four decades due to their well-documented and clinically relevant anti-tumour properties.Acquired resistance is a challenge for the clinical use of these compounds and there is a continuing need to search for potential new therapeutic agents. Herein, the potential of two metal-basedcompounds containing chelated1,10-phenanthroline (1,10-Phen), one manganese-based (CMPD 73)andonecopper-based (CMPD 74), to act as novel therapeutic agents is explored.CMPD 73 displayed high micromolar (IC50>100μM) cytotoxic properties againstvarious cell systems but interestingly displayed increased cytotoxicity against ovarian (A2780), lung (A549) and cisplatin resistant mesothelioma cells(IC5040-50μM). CMPD 74 was equally cytotoxic against …
Recognising The Place Of Food Tourism In Ireland: An Autoethnographic Perspective, John D. Mulcahy
Recognising The Place Of Food Tourism In Ireland: An Autoethnographic Perspective, John D. Mulcahy
Doctoral
This is an autoethnographic account, utilising prior publications, of my role in positioning food as a critical ingredient in Ireland’s tourism policy and strategy since 2009. As the architect and instigator of this project, my priorities were threefold: first, working from the ground up identifying local activists across the food tourism landscape to create an active and vibrant network; second, providing thought leadership for food tourism; and third, encouraging and funding others to conduct and disseminate similar research. I have chosen six book chapters, published as a result of my advocacy strategy, for this PhD by prior publication. They are …
Development Of Assessment Tools Of Package/Product Systems For A Sustainable Food Chain, Kompal Joshi
Development Of Assessment Tools Of Package/Product Systems For A Sustainable Food Chain, Kompal Joshi
Doctoral
Post-harvest life of fresh produce is limited due to high metabolic activity and microbial spoilage. Modified atmosphere packaging (MAP) has proven to be one of the most effective techniques to extend the shelf life of fresh produce commercially. Obtaining of an optimum concentration of oxygen and carbon dioxide inside the package depends upon the product properties, the environmental conditions of the cold chain, the permeable film, some of which are subjected to natural variability during the food distribution chain. This variability may generate produce that is out of specification that will lead to food waste. Uncertainty analysis of this problem …
Development Of Methodologies For Raman Spectral Analysis Of Human Saliva For Detection Of Oral Cancer, Genecy Calado
Development Of Methodologies For Raman Spectral Analysis Of Human Saliva For Detection Of Oral Cancer, Genecy Calado
Doctoral
Oral cancer is one of the most common malignancies worldwide, with over 350,000 to 400,000 new cases reported each year. Early detection, followed by appropriate treatment, can increase cure rates to 80 or 90%, and greatly improve the quality of life by minimising extensive, debilitating treatments. Usually, the clinical diagnosis of most head and neck neoplasms, including oral cancer, is performed through time-consuming and invasive biopsies followed by histological examination of the excised tissue and may present psychological trauma and risk of infection to patients. In addition, histological grading can be subjective, as it is based on subtle morphological changes. …
Novel Lipase(S): Application In Biodiesel Production From Wastewater Grown Microalgae, Priyanka Anilkumar
Novel Lipase(S): Application In Biodiesel Production From Wastewater Grown Microalgae, Priyanka Anilkumar
Doctoral
Lipase-basedcatalysis in organic solvents offerseveraladvantages and,therefore, havebeen widely researched and applied. Nature provides a vast microbial enzyme pool thatcan be easily bio-discovered through the targeted exploration of existing extremophiles.Among the large number of bacterial lipases, those from species like Geotrichum, Bacillus, Pseudomonas, BurkholderiandStreptomyceshave shownadequate stability forbiosynthetic application. In this study, severalbacterial strains isolated from soils in the Dublin and Laois regionsofIrelandwere screened forpresence ofsolvent stable lipases.Fivebacterialstrains producing most solvent stable lipase(s) were identified asPseudomonas sp. BIM B-86, Sphingomonas sp., Listeria monocytogenes, Pseudomonas reinekeiand Pseudomonas brennerivia 16S rRNA sequencing.Amonst thesefive strains, new lipolytic enzymes from only two strains of Pseudomonassp. i.e. …
Plasma Functionalised Liquids: From Bench To Prototype For Safe Fresh Food Preservation, Uta Schnabel
Plasma Functionalised Liquids: From Bench To Prototype For Safe Fresh Food Preservation, Uta Schnabel
Doctoral
Fresh-cut produce such as lettuce may contain a very high microbial load, including human pathogens. Therefore, the need for antimicrobial interventions at post-harvest stages to prevent microbial growth is evident. Sanitation steps based on non-thermal plasmas at atmospheric pressure opens up innovative food processing possibilities by application at different points along the food chain; for production, modification and preservation, as well as in package treatment of plant- and animal-based foods. Plasma differs from the gaseous state of matter by a certain amount of free charge carriers caused by ionisation processes of the gas atoms and molecules due to the supply …