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49th. Annual Food Science And Technology Conference: Book Of Abstracts, Ifsti: Institute Of Food Science & Technology In Ireland, Jesus Maria Frias, Graham O'Neill, Kaye Burgess, Catherine Barry-Ryan Jan 2020

49th. Annual Food Science And Technology Conference: Book Of Abstracts, Ifsti: Institute Of Food Science & Technology In Ireland, Jesus Maria Frias, Graham O'Neill, Kaye Burgess, Catherine Barry-Ryan

Conference papers

The Institute of Food Science and Technology of Ireland, Technological University Dublin and the Environmental Sustainability Health Institute (ESHI) will host the 49th Annual Food Science & Technology Conference virtually on Tuesday 15th December 2020. This years conference will focus on the topic of food sustainability and has six themes. • Alternative food sources and processing • Targeted nutrition • Bioeconomy • Food Security • Improving Sustainability of Food Systems • Improving the Healthiness of Food Systems 70 submissions were received and the Scientific Committee selected 16 of them for Oral presentations. Following the long lasting tradition of this conference, …


Privileged Structure: Novel Indane Scaffolds As Potential Anticancer And Anti-Inflammatory Agents, Kit Chan, Tao Zhang, Vilmar Cláudio Bandero-Filho, Andrew Moriarty, Paul Mccormick, Brian Mehigan, Cathcart Mary Clare, Robin Daly, Breandán Kennedy, Jacintha O'Sullivan, Neil Frankish, Helen Sheridan Jan 2020

Privileged Structure: Novel Indane Scaffolds As Potential Anticancer And Anti-Inflammatory Agents, Kit Chan, Tao Zhang, Vilmar Cláudio Bandero-Filho, Andrew Moriarty, Paul Mccormick, Brian Mehigan, Cathcart Mary Clare, Robin Daly, Breandán Kennedy, Jacintha O'Sullivan, Neil Frankish, Helen Sheridan

Conference papers

The identification and use of “privileged structures” can increase the reliability and shorten the process in the drug discovery and drug design (a-b). Indane scaffolds occur in various natural products and they constitute the privileged structure that is ubiquitous in many biologically and pharmaceutically active molecules (c-e). Our research group has been working on the synthesis and pharmacological activity of nature identical and synthetically modified indanes and indanones for 20 years. In the current study, the molecular design is centred on elaboration of a fern derived bioactive pharmacophore. The fern is used in traditional Taiwanese medicine to treat inflammation, allergy, …