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Full-Text Articles in Life Sciences

Physicochemical Differences Between Camelid Single-Domain Antibodies And Mammalian Antibodies, Nazli Eda Eski̇er, Doğa Eski̇er, Esi̇n Fi̇ruzan, Si̇bel Kalyoncu Dec 2023

Physicochemical Differences Between Camelid Single-Domain Antibodies And Mammalian Antibodies, Nazli Eda Eski̇er, Doğa Eski̇er, Esi̇n Fi̇ruzan, Si̇bel Kalyoncu

Turkish Journal of Biology

Background/aim: In recent years, single-domain antibodies, also known as nanobodies, have emerged as an alternative to full immunoglobulin Gs (IgGs), due to their various advantages including increased solubility, faster clearance, and cheaper production. Nanobodies are generally derived from the variable domain of the camelid heavy-chain-only immunoglobulin Gs (hcIgGs). Due to the high sequence homology between variable heavy chains of camelids (VHHs) and humans (VHs), hcIgGs are ideal candidates for nanobody development. However, further examination is needed to understand the structural differences between VHs and VHHs. This analysis is essential for nanobody engineering to mitigate potential immunogenicity while preserving stability, functionality, …


Chemical And Biochemical Advantages Of The 'Hicaznar' Pomegranate Variety Over 'Katina' And 'Suruc' Varieties Grown In The Same Ecology, Beki̇r Erol Ak, Di̇cle Roza Sayi̇ner, İbrahi̇m Hali̇l Hati̇poğlu, Bi̇rgül Di̇kmetaş Aug 2023

Chemical And Biochemical Advantages Of The 'Hicaznar' Pomegranate Variety Over 'Katina' And 'Suruc' Varieties Grown In The Same Ecology, Beki̇r Erol Ak, Di̇cle Roza Sayi̇ner, İbrahi̇m Hali̇l Hati̇poğlu, Bi̇rgül Di̇kmetaş

Turkish Journal of Agriculture and Forestry

Pomegranate cultivation has spread to various parts of the world. Pomegranate has been grown almost anywhere in the world, mostly in Iran, India, China, Turkey and the United States. ‘Hicaznar’, ‘Katina’ and ‘Suruç’ pomegranate varieties were used as materials in this study. Analyses of antioxidants, sugars, anthocyanins, organic acids, and colourless phenolic compounds in the juices of these fruits were performed by HPLC and DPPH methods. According to our findings, the highest antioxidant capacity was found in ‘Hicaznar’ variety (19.42 mmol trolox L–1). ‘Hicaznar’ variety had high sugar composition in terms of glucose, fructose, and total sugars while the sucrose …


Physicochemical Properties Of Turkish Green Tea Powder: Effects Of Shooting Period, Shading, And Clone, Ayhan Topuz, Cüneyt Di̇nçer, Mehmet Torun, İsmai̇l Tontul, Hi̇lal Şahi̇n Nadeem, Ayhan Haznedar, Feramuz Özdemi̇r Jan 2014

Physicochemical Properties Of Turkish Green Tea Powder: Effects Of Shooting Period, Shading, And Clone, Ayhan Topuz, Cüneyt Di̇nçer, Mehmet Torun, İsmai̇l Tontul, Hi̇lal Şahi̇n Nadeem, Ayhan Haznedar, Feramuz Özdemi̇r

Turkish Journal of Agriculture and Forestry

This study aimed to determine the physicochemical properties of the green tea powders produced from 2 different Turkish tea [Camellia sinensis (L.) O.Kuntze] clones (Derepazarı 7 and Fener) grown under different shade levels and harvested during 2 consecutive shooting periods. Moisture, ash, crude fiber, and total phenolic contents of the green tea powders were determined based on the experimental factors. Products were also evaluated for their water activity, bulk density, particle size, color, extraction yield, and antioxidant activity. The shooting period, specific to Turkish tea cultivation, showed remarkable effects on the main quality parameters of the green tea powders. It …