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Full-Text Articles in Life Sciences
Investigation Of The Effect Of Silymarin On Oxidative Dna Damageand Inflammatory Markers In Ischemia/Reperfusion Injuryfollowing Experimental Testicular Torsion/Detorsion In Rats, Saadet Belhan, Serkan Yildirim, Caner Kayikci, Ahmet Ufuk Kömüroğlu, Uğur Özdek, Yağmur Kuşcu
Investigation Of The Effect Of Silymarin On Oxidative Dna Damageand Inflammatory Markers In Ischemia/Reperfusion Injuryfollowing Experimental Testicular Torsion/Detorsion In Rats, Saadet Belhan, Serkan Yildirim, Caner Kayikci, Ahmet Ufuk Kömüroğlu, Uğur Özdek, Yağmur Kuşcu
Turkish Journal of Zoology
The aim of the present study was to clarify the effects of silymarin on experimental testicular ischemia / reperfusion injury. A total of 40 Wistar albino rats (10-12 weeks of age, weighing 280-300 g) were randomly divided into five groups. Control group: No surgical procedures were performed. Torsion 3 h / detorsion 3 h group; torsion 3 h / detorsion 24 h group; torsion 3 h / detorsion 3 h + silymarin (250 mg/kg) group; and torsion 3 h / detorsion 24 h + silymarin (250 mg/kg) group. In the study, 720° torsion was applied to the left testicle. At …
Investigation Of Protective Effects Of Lithium Borate On Spermatogenesis And Testes Histopathology Against Cadmium-Induced Acute Toxicity In Rats, Serkan Yildirim, Fati̇h Çağlar Çeli̇kezen, Saadet Belhan, Gökhan Oto, Gi̇zem Eser, Emi̇n Şengül, Dursunali̇ Çinar
Investigation Of Protective Effects Of Lithium Borate On Spermatogenesis And Testes Histopathology Against Cadmium-Induced Acute Toxicity In Rats, Serkan Yildirim, Fati̇h Çağlar Çeli̇kezen, Saadet Belhan, Gökhan Oto, Gi̇zem Eser, Emi̇n Şengül, Dursunali̇ Çinar
Turkish Journal of Zoology
In this study, protective effects of lithium borate (LTB) on spermatogenesis as well as histopathological and immunohistochemical findings of testes in experimentally induced acute Cadmium (Cd) toxicity in rats were determined. Twenty-eight male Wistar albino rats, were used, weighing 200-220 g. Rats were randomly divided into 4 groups: Control, Cd, LTB, and LTB + Cd. Rats were anesthetized with ketamine at the end of the sixth day, blood was taken from their hearts, and the rats were decapitated. Typically, the control and LTB groups exhibited similar values. Compared with those observed for the control group, the sperm morphology (i.e. abnormal …
Effects Of Aluminum, Copper, And Titanium Nanoparticles Onsome Blood Parameters In Wistar Rats, Esi̇n Gülnaz Canli, Mustafa Canli
Effects Of Aluminum, Copper, And Titanium Nanoparticles Onsome Blood Parameters In Wistar Rats, Esi̇n Gülnaz Canli, Mustafa Canli
Turkish Journal of Zoology
In this study, Al2O3, CuO, and TiO2 nanoparticles (NPs) were individually administered to 60 mature female rats via oral gavage (0, 0.5, 5, and 50 mg/kg b.w. per day) for 14 days and then responses of ATPases in the erythrocytes, total oxidant status (TOS), total antioxidant status (TAS), and liver enzyme (alkaline phosphatase, ALP; alanine transaminase, ALT; aspartate transaminase, AST) levels in the serum were determined. There were sharp decreases in Na,K-ATPase activity in the erythrocytes following NP exposures. All doses of CuO caused significant (P < 0.05) inhibitions in Na,K-ATPase activity (up to 94%), while only higher doses of Al2O3 and TiO2 inhibited (76%-80%) the activity of Na,K-ATPase. Oppositely, the activities of Ca-ATPase (up to 274%) and Mg-ATPase (up to 290%) increased significantly following TiO2 exposures. TOS levels significantly increased following Al2O3 (167%) and CuO (240%) exposures, though TAS levels did not change significantly in any of the exposure groups. The levels of ALP, AST, and ALT increased following NP administrations. Ti-NP increased the levels of all liver enzymes in the serum (up to 84%), while Al-NP (58%) and Cu- NP (43%) increased only ALP levels. The present study demonstrated evidence of the toxic effects of NPs, as they altered the measured parameters in the blood, and suggests further research to better understand the environmental fate of NPs.
Inhibitory Effect Of Bursa Propolis On Dental Caries Formation In Rats Inoculated With Streptococcus Sobrinus, Gamze Bozcuk Erdem, Seval Ölmez
Inhibitory Effect Of Bursa Propolis On Dental Caries Formation In Rats Inoculated With Streptococcus Sobrinus, Gamze Bozcuk Erdem, Seval Ölmez
Turkish Journal of Zoology
The effect of propolis on the growth of Lactobacillus casei RSKK 591, Streptococcus mutans NCTC 10449 and Streptococcus sobrinus DSN sobrinus 20742 was investigated in vitro. Bursa propolis had the most inhibitory effect on S. sobrinus. The effect of Bursa propolis on rats inoculated with S. sobrinus was also studied. In rats inoculated with the bacteria and given propolis, the severity of sulcal enamel and superficial dentine lesions was significantly less than that in the control group, but colony forming unit numbers and the caries scores in other levels were not different. Weight gains, and the food and water consumption …
Dermal Efficacy Of Bendiocarb On Mammals, Used For Mosquito Control In Çukurova, Ayfer Pazarbaşi, Mülki̇ye Kasap, Hali̇l Kasap
Dermal Efficacy Of Bendiocarb On Mammals, Used For Mosquito Control In Çukurova, Ayfer Pazarbaşi, Mülki̇ye Kasap, Hali̇l Kasap
Turkish Journal of Zoology
Inhibitory effect of bendiocarb on serum and whole blood cholinesterase activities of rats was investigated in laboratory conditions, bendiocarb a carbamate insecticide, was applied dermally to the rats. The concentrations of insecticide (80% WP) were choosen in accordance with the spray dosages used for mosquito control and the LD_{50} dermal dosages for rats. In vitro inhibition of serum cholinesterase activity was determined by using technical bendiocarb in the same dermal dosages. Both in vitro and in vivo dermal studies showed that there is a negative correlation between bendiocarb (80% WP) concentrations and enzyme activities. Application of one dose of bendiocarb …