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Articles 1 - 3 of 3
Full-Text Articles in Life Sciences
Institutional Design And Governance In Microbial Research Commons, Charlotte Hess
Institutional Design And Governance In Microbial Research Commons, Charlotte Hess
Libraries' and Librarians' Publications
Presentation slides on institutional design and governance to facilitate a global research commons for microbiology delivered at the International Symposium on Designing the Microbial Research Commons, sponsored by the National Academy of Sciences, Washington, DC, 8-9 October 2009.
Are “Quantitative” Pits Still Necessary At Hubbard Brook?, Chris E. Johnson
Are “Quantitative” Pits Still Necessary At Hubbard Brook?, Chris E. Johnson
Civil and Environmental Engineering
No abstract provided.
Regulation Of Heterochromatin Assembly On Unpaired Chromosomes During Caenorhabditis Elegans Meiosis By Components Of A Small Rna-Mediated Pathway, Xingyu She, Xia Xu, Alexander Fedotov, William G. Kelly, Eleanor M. Maine
Regulation Of Heterochromatin Assembly On Unpaired Chromosomes During Caenorhabditis Elegans Meiosis By Components Of A Small Rna-Mediated Pathway, Xingyu She, Xia Xu, Alexander Fedotov, William G. Kelly, Eleanor M. Maine
Biology - All Scholarship
Many organisms have a mechanism for down regulating the expression of non-synapsed chromosomes and chromosomal regions during meiosis. This phenomenon is thought to function in genome defense. During early meiosis in Caenorhabditis elegans, unpaired chromosomes (e.g., the male X chromosome) become enriched for a modification associated with heterochromatin and transcriptional repression, dimethylation of histone H3 on lysine 9 (H3K9me2). This enrichment requires activity of the cellular RNA-directed RNA polymerase, EGO-1. Here we use genetic mutation, RNA interference, immunofluorescence microscopy, fluorescence in situ hybridization, and molecular cloning methods to identify and analyze three additional regulators of meiotic H3K9me2 distribution: CSR-1 (a …