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South Dakota State University

Electronic Theses and Dissertations

2018

Gut health

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Evaluation Of Microbially-Converted Soybean Meal As An Alternative To Fishmeal In Weaned Pig Diets, Sue Sinn Jan 2018

Evaluation Of Microbially-Converted Soybean Meal As An Alternative To Fishmeal In Weaned Pig Diets, Sue Sinn

Electronic Theses and Dissertations

Digestibility values determined in growing pigs may not apply to nursery pigs; thus, standardized ileal digestibility (SID) of AA in MCSBM and fishmeal (FM) were determined using 30 ± 1.6 kg BW ileal-cannulated barrows (n = 6) and 9.8 ± 1.2 kg BW barrows (n = 37; serial slaughter). Experimental diets included MCSBM, FM, and nitrogen-free where FM and MCSBM were included as the sole protein source. The SID of AA was 3-5% lower in MCSBM than FM when fed to 30 kg pigs. The SID of Arg and Met was greater (P < 0.05) in MCSBM than FM when fed to 10 kg pigs. The SID of AA was 12-20% lower in FM when fed to 10 versus 30 kg pigs but only 3-9% lower in MCSBM. A total of 336 barrows and gilts were weaned at 21 d of age (initial BW 6.1 ± 0.8 kg) and used in a performance trial. Pens of pigs were assigned to one of 6 experimental diets (8 pens/diet in two blocks). Treatment diets were fed in Phase I (7 d) and Phase II (14 d) with all pigs fed a common Phase III diet (14 d). Experimental diets included: 1) negative control (NEG) containing corn, soybean meal and whey, 2) NEG + acidifier (NEGA), 3) NEG + FM (POS), 4) POS + acidifier (POSA), 5) NEG + MCSBM (MCSBM), and 6) MCSBM + acidifier (MCSBMA). The FM and MCSBM were included at 7.5% and 5.0% in Phase I and II diets, respectively. Diets were formulated to meet the standard nutrient requirements for weaned pigs. Pig BW and feed disappearance was measured weekly and fecal scores were measured daily for the first 14 d postweaning as an indicator of PWDS. Performance (BW, ADG, ADFI, and G/F) was not significantly different among treatments. Treatment for PWDS occurred on different days in each block. Analysis of fecal score was completed separately by block. Pigs fed the NEG diets had higher (P = 0.02) fecal scores than pigs fed the POS diets on d 2 and 3 (block 1) and higher (P < 0.05) than pigs fed MCSBM or POS diets and diets with dietary acidifier on d 6 and 3 (block 2). At the end of Phase I and II, one pig/pen was humanely euthanized for digesta and tissue collection. Digesta pH was measured in the pyloric region of the stomach, duodenum, middle jejunum, ileum, cecum, and middle colon. There was an effect of location (P < 0.0001), where the pH was lowest in the stomach and increased until the ileum with a slight dip in the cecum and increased in the colon. There was no effect of ingredient, dietary acid, or their interaction within the gastrointestinal tract. At the end of Phase I, pigs fed NEG and POSA diets had similar pH (P > 0.10) from the stomach to the duodenum, …


Evaluation Of Berberine As An Alternative To Antibiotics In Nursery Pig Diets, Emily Scholtz Jan 2018

Evaluation Of Berberine As An Alternative To Antibiotics In Nursery Pig Diets, Emily Scholtz

Electronic Theses and Dissertations

Pig weaning process results in reduced growth performance and gut health of weaned pigs. Antibiotics can be added in diets for weaned pigs to improve growth performance and gut health, but their use is being discouraged because they can lead to development of antimicrobial resistant microorganisms. Thus, there is need for alternatives to antibiotics in diets for weaned pigs. The overall goal of this thesis research was to determine the effects of plant extracts (berberine, quercetin, and allyl isothiocyante [AITC]) as alternatives to antibiotics in weaned pig diets. The first objective of the research was to determine in vitro antimicrobial …