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Full-Text Articles in Life Sciences
Integrating Node Embeddings And Biological Annotations For Genes To Predict Disease-Gene Associations, Sezin Kircali Ata, Le Ou-Yang, Yuan Fang, Chee-Keong Kwoh, Min Wu, Xiao-Li Li
Integrating Node Embeddings And Biological Annotations For Genes To Predict Disease-Gene Associations, Sezin Kircali Ata, Le Ou-Yang, Yuan Fang, Chee-Keong Kwoh, Min Wu, Xiao-Li Li
Research Collection School Of Computing and Information Systems
Background: Predicting disease causative genes (or simply, disease genes) has played critical roles in understandingthe genetic basis of human diseases and further providing disease treatment guidelines. While various computationalmethods have been proposed for disease gene prediction, with the recent increasing availability of biologicalinformation for genes, it is highly motivated to leverage these valuable data sources and extract useful information foraccurately predicting disease genes. Results: We present an integrative framework called N2VKO to predict disease genes. Firstly, we learn the nodeembeddings from protein-protein interaction (PPI) network for genes by adapting the well-known representationlearning method node2vec. Secondly, we combine the learned node …
The European Union And The Establishment Of Marine Protected Areas In Antarctica, Nengye Liu
The European Union And The Establishment Of Marine Protected Areas In Antarctica, Nengye Liu
Research Collection Yong Pung How School Of Law
This paper examines how the EU can best use its powers to establish marine protected areas (MPAs) in Antarctica. It first discusses the EU’s role in Antarctic governance and legal basis for the EU’s actions, with particular focus on the pending Joined Cases C-625/15 and C-659/16 at the Court of Justice of the European Union. Secondly, the paper analyses the negotiation process of the EU’s MPA proposals in the Southern Ocean within the Commission for the Conservation of Antarctic Marine Living Resources. Thirdly, it provides suggestions regarding the EU’s potential actions that might help achieve proposed Antarctic MPAs.
Reframing The Sustainable Development Goals To Achieve Sustainability In The Anthropocene — A Systems Approach, Michelle Mei Ling Lim, Peter Sogaard Jorgensen, Carina Wyborn
Reframing The Sustainable Development Goals To Achieve Sustainability In The Anthropocene — A Systems Approach, Michelle Mei Ling Lim, Peter Sogaard Jorgensen, Carina Wyborn
Research Collection Yong Pung How School Of Law
Griggs et al. (2013) redefine sustainable development as “development that meets the needs of the present while safeguarding Earth’s life-support system, on which the welfare of current and future generations depend.” We recommend this as the end goal that the United Nations sustainable development goals (SDGs) should strive to achieve. Integration across the SDGs is less than what is required from a science perspective. Effective implementation of the SDGs will require States to attend to trade-offs and overlaps. We argue that continuous failure to address integration within the SDGs will jeopardize realization of this ultimate end goal. Therefore, we adopt …
Will China Build A Green Belt And Road In The Arctic, Nengye Liu
Will China Build A Green Belt And Road In The Arctic, Nengye Liu
Research Collection Yong Pung How School Of Law
This article aims to shed light on two questions: what are the implications of China's Belt and Road Initiative (BRI) for Arctic governance? And what are the environmental implications of the BRI for the Arctic? The article first discusses the interaction between China's BRI and Arctic policy, examining the vision that China would like to use the BRI to shape Arctic governance. The article focuses on the environmental components of the BRI. It explores whether China's current regulatory regimes are sufficient to help ensure a green Belt and Road in the Arctic.
Impact Of Electrification On Children's Nutritional Status In Rural Bangladesh, Tomoki Fujii, Abu S. Shonchoy, Sijia Xu
Impact Of Electrification On Children's Nutritional Status In Rural Bangladesh, Tomoki Fujii, Abu S. Shonchoy, Sijia Xu
Research Collection School Of Economics
Access to electricity has the potential to improve the nutritional status of children by a variety of pathways such as increased wealth, reduced fertility through the change in time use, spread of information through technology such as TV, and improved health care services. Yet, the relationship between electrification and children’s nutritional status is rarely explored in the literature. We attempt to fill this lacuna by offering microeconometric evidence from rural Bangladesh, where a rapid expansion of electrification and significant improvement in children’s nutritional status were observed in the past two decades. We find that access to electricity has a positive …