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Full-Text Articles in Life Sciences
Homology Modeling And In Silico Analysis Of Cox From Channa Punctata, Azhaguraj Ramakrishnan
Homology Modeling And In Silico Analysis Of Cox From Channa Punctata, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
The Cytochrome c oxidase (COX) region of mitochondrial DNA is the most studied region of the fish mitochondrial genome. COX is one of the largest protein coding genes of metazoan mitochondrial genome.COX (E.C.1.9.3.1) is the terminal member of the respiratory chain catalyzing the reduction of dioxygen to water by ferrocytochrome C. A 19.927 kDa COX has been characterized in Channa punc-tata where COX III dimensional structure was generated using Deep View/ Swiss Pdp Viewer 3.7(Sps) by homol-ogy modeling, predicted model was validated in RAM-PAGE Server and COX secondary structure is predicted by PSIPRED, PHYRE and TNHMM Server. Protein statics was …
Abd: Advanced Biotechnological Directory For Protein Sequence And Structure Analysis, Azhaguraj Ramakrishnan
Abd: Advanced Biotechnological Directory For Protein Sequence And Structure Analysis, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
Over the past decades, a number of computational tools for structure prediction have been developed. It is critical that the biological community is aware of such tools and is able to interpret their results in an informed way. Rapid increase in protein sequence information from genome sequencing projects demand the intervention of bioinformatics tools to recognize interesting gene products and associated function often multiple algorithms need to be employed to improve accuracy in prediction and several structure prediction. Here we report the availability of an ABD as a bioinformatics online package dedicated for Insilco analysis of protein sequence and structure …
Predication Of Biological Activity Of Algal Antitumor Drugs Using Pass, Azhaguraj Ramakrishnan
Predication Of Biological Activity Of Algal Antitumor Drugs Using Pass, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
The computer system PASS provides simultaneous predication of several hundreds of biological activity types of any drug like compounds. Over the past decade seaweeds have become an interesting source of new classes of pharmacologically active natural products. The majority of biologically active compounds have both pharmacotherapeutic and side/toxic actions. To estimate general efficacy and safety of the molecules under study, their biological potential should be thoroughly evaluated. In this study the PASS (Predication of activity spectra for substances)computer program, which is able to simultaneously predict more than one thousand biological and toxicological activities from only the structural formulas of the …