Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Phenotypic Effects Of Leptin In An Ectotherm: A New Tool To Study The Evolution Of Life Histories And Endothermy?, Richard L. Londraville, Michelle L. Balk, Peter H. Niewiarowski
Phenotypic Effects Of Leptin In An Ectotherm: A New Tool To Study The Evolution Of Life Histories And Endothermy?, Richard L. Londraville, Michelle L. Balk, Peter H. Niewiarowski
Dr. Peter H. Niewiarowski
Leptin is a hormone that regulates energy expenditure and body mass in mammals, and it has attracted considerable attention because of its potential in treating human obesity. Comprehensive data from both pathological and non-pathological systems strongly support a role for leptin in regulating energy metabolism, in thermoregulation and in regulating the onset of puberty. We report here that daily injections of recombinant murine leptin in fence lizards (Sceloporus undulatus) produce phenotypic effects similar to those observed when leptin injections are given to mice, Lizards injected with leptin had body temperatures 0.6 degrees C higher, ate 30 % less food and …
Phenotypic Effects Of Leptin In An Ectotherm: A New Tool To Study The Evolution Of Life Histories And Endothermy?, Richard L. Londraville, Michelle L. Balk, Peter H. Niewiarowski
Phenotypic Effects Of Leptin In An Ectotherm: A New Tool To Study The Evolution Of Life Histories And Endothermy?, Richard L. Londraville, Michelle L. Balk, Peter H. Niewiarowski
Richard L. Londraville
Leptin is a hormone that regulates energy expenditure and body mass in mammals, and it has attracted considerable attention because of its potential in treating human obesity. Comprehensive data from both pathological and non-pathological systems strongly support a role for leptin in regulating energy metabolism, in thermoregulation and in regulating the onset of puberty. We report here that daily injections of recombinant murine leptin in fence lizards (Sceloporus undulatus) produce phenotypic effects similar to those observed when leptin injections are given to mice, Lizards injected with leptin had body temperatures 0.6 degrees C higher, ate 30 % less food and …