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Life Sciences Commons™

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Selected Works

2008

Development

Articles 1 - 3 of 3

Full-Text Articles in Life Sciences

Word Sense Disambiguation In Biomedical Ontologies With Term Co-Occurrence Analysis And Document Clustering, Bill Andreopoulos, Dimitra Alexopoulou, Michael Schroeder Sep 2008

Word Sense Disambiguation In Biomedical Ontologies With Term Co-Occurrence Analysis And Document Clustering, Bill Andreopoulos, Dimitra Alexopoulou, Michael Schroeder

William B. Andreopoulos

With more and more genomes being sequenced, a lot of effort is devoted to their annotation with terms from controlled vocabularies such as the GeneOntology. Manual annotation based on relevant literature is tedious, but automation of this process is difficult. One particularly challenging problem is word sense disambiguation. Terms such as |development| can refer to developmental biology or to the more general sense. Here, we present two approaches to address this problem by using term co-occurrences and document clustering. To evaluate our method we defined a corpus of 331 documents on development and developmental biology. Term co-occurrence analysis achieves an …

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The Effects Of Prenatal Stress On Motivation In The Rat Pup, Howard Cromwell Dec 2007

The Effects Of Prenatal Stress On Motivation In The Rat Pup, Howard Cromwell

Howard Casey Cromwell

Exposure to prenatal stress (PNS) has been shown to induce a set of psychological and behavioral changes in developing offspring. We used the rodent model to investigate whether PNS produces changes in the ability of the pup to express social motivation.We used a set of behavioral tasks including monitoring ultrasonic vocalizations after isolation, a conditioned place preference, and a novel and familiar odor approach test. Pregnant Long–Evans rats were exposed to an unpredictable, variable stressor twice daily during the third week of gestation. Isolation vocalizations were assessed on postnatal day (PND) 10. Pup affinity for the dam was evaluated on …

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La Desnutrición Infantil En México En Perspectiva Internacional: 1988-2006, Rodrigo Garcia-Verdu Dec 2007

La Desnutrición Infantil En México En Perspectiva Internacional: 1988-2006, Rodrigo Garcia-Verdu

Rodrigo Garcia-Verdu

No abstract provided.

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