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Selected Works

Aydin Nazmi

2011

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Cross-Sectional And Longitudinal Associations Of Neighborhood Characteristics With Inflammatory Markers: Findings From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana Diez Roux, Nalini Ranjit, Teresa E. Seeman, Nancy S. Jenny Jan 2011

Cross-Sectional And Longitudinal Associations Of Neighborhood Characteristics With Inflammatory Markers: Findings From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana Diez Roux, Nalini Ranjit, Teresa E. Seeman, Nancy S. Jenny

Aydin Nazmi

We investigated cross-sectional associations of neighborhood deprivation, problems, safety, and cohesion with circulating levels of fibrinogen, interleukin-6, and C-reactive protein (n=5370) and longitudinal associations with changes in IL-6 over a 3–4 year period (n=946). In cross-sectional analyses, higher levels of neighborhood deprivation and problems were associated with higher levels of all three inflammatory markers, whereas higher levels of safety were associated with lower levels. Fibrinogen remained associated with all neighborhood characteristics except cohesion and IL-6 remained associated with safety after adjustment for race and SES. In longitudinal analyses, higher levels of neighborhood deprivation and problems, and lower levels of safety …


The Influence Of Persistent Pathogens On Circulating Levels Of Inflammatory Markers: A Cross-Sectional Analysis From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana V. Diez-Roux, Nancy S. Jenny, Michael Y. Tsai, Moyses Szklo, Allison E. Aiello Jan 2011

The Influence Of Persistent Pathogens On Circulating Levels Of Inflammatory Markers: A Cross-Sectional Analysis From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana V. Diez-Roux, Nancy S. Jenny, Michael Y. Tsai, Moyses Szklo, Allison E. Aiello

Aydin Nazmi

Background: Systemic inflammation is linked to cardiovascular risk, but the influence of persistent pathogens, which are conventionally dichotomously categorized, on circulating levels of inflammatory markers is not clear. Antibody levels of pathogens have not been examined in relation to inflammation. Methods: Using data from a subsample of the Multi-Ethnic Study of Atherosclerosis, we examined circulating levels of interleukin-6 (IL-6), C-reactive protein (CRP) and fibrinogen in relation to five common persistent pathogens: cytomegalovirus, herpes simplex virus-1, Hepatitis A virus, Helicobacter pylori and Chlamydia pneumoniae. We tested the hypothesis that the number of seropositive pathogens (based on conventional cut-off points) would not …