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Using Hydroxyapatite From Fish Scales To Prepare Chitosan/Gelatin/Hydroxyapatite Membrane: Exploring Potential For Bone Tissue Engineering, Yi-Cheng Huang, Hao-Wen Chu

Journal of Marine Science and Technology

Concerns have recently been raised about the treatment and use of hydroxyapatite, an important component of fish scale. The goal of this investigation is to evaluate the feasibility of using hydroxyapatite extracted from fish scale (FHAP) for bone tissue engineering. FHAP or sintered FHAP (sFHAP) was added to chitosan/gelatin (CS/GEL) mixture to prepare membrane. The effect of FHAP and sFHAP on the physical and chemical properties of the membrane and their affinities towards MG63 cells were studied. Accordingly, the prepared CS/GEL/FHAP membrane was characterized by FTIR (ATRFTIR) and SEM. Following sintering at 800°C for 4 h, the CS/GEL/sFHAP membrane had …