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Full-Text Articles in Life Sciences
Untangling The Effects Of Biosynthetic And Metabolic Rates On Oxidative Cellular Damage In An Insect Model, Nikki Jihui Gomez
Untangling The Effects Of Biosynthetic And Metabolic Rates On Oxidative Cellular Damage In An Insect Model, Nikki Jihui Gomez
Masters Theses
“Previously, a theoretical model for unravelling the entwined effects of metabolic and biosynthetic rates on oxidative cellular damage accumulation during an animal’s growth period was developed and tested in hornworms (Manduca sexta larvae). In theory, if an animal had unrestricted amounts of energy and a high repair efficiency, they could repair most of the oxidative cellular damage accumulated, regardless of how their metabolic rate varies. However, organisms have a finite amount of energy that is allocated to repair and, during the animal’s development period, a considerable amount of energy goes towards growth eliciting a tradeoff between biosynthesis and repair. …
Fluid Flow In A Krogh Cylinder: A Model For A Single Capillary And Surrounding Tissue, Xianjie Qiu
Fluid Flow In A Krogh Cylinder: A Model For A Single Capillary And Surrounding Tissue, Xianjie Qiu
Masters Theses
"A model describing the flow of plasma from the capillaries to the interstitial space in the extravascular tissue and back into the capillaries is constructed and solved. The flow through the tissue or the interstitial spaces is described by the Brinkman equation for porous medium, modified to account for the presence of cells considered as spheres. The flow of blood through the capillaries is considered to be that of a Newtonian fluid. The flow between capillary and tissue is coupled by the permeability of the capillary wall. The nature of flow and its magnitude was found to be highly dependent …
Comparative Toxicology Of Nio And Ni(Oh)₂ Nanoparticles, Melissa Hope Cambre
Comparative Toxicology Of Nio And Ni(Oh)₂ Nanoparticles, Melissa Hope Cambre
Masters Theses
“Understanding the potential toxicity of nanoparticles (NPs) is important to ensure that these new products do not impose harmful effects to human and environmental health. Paper I is a literature review in which we discuss characteristics of nanomaterials, with an emphasis on transition metal oxide nanoparticles that influence cytotoxicity. Identification of those properties may lead to the design of more efficient and safer nanosized products for various industrial purposes and provide guidance for assessment of human and environmental health risk. We then investigate biochemical and molecular mechanisms of cytotoxicity that include oxidative stress-induced cellular events and alteration of the pathways …