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Mississippi State University

Theses and Dissertations

RNA-seq

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Expression Analysis Of Micrornas And Microrna-Like Rnas In Aspergillus Flavus-Infected Aflatoxin Resistant And Susceptible Maize Inbred Lines, Amanda Benton Harper Dec 2018

Expression Analysis Of Micrornas And Microrna-Like Rnas In Aspergillus Flavus-Infected Aflatoxin Resistant And Susceptible Maize Inbred Lines, Amanda Benton Harper

Theses and Dissertations

Corn (Zea mays) is frequently infected by a soil fungal pathogen Aspergillus flavus. The fungus produces aflatoxins, which cause liver cancer. Maize inbred lines that are resistant to infection by A. flavus have been developed, and these inbred lines provide excellent models for studying molecular mechanisms of maize resistance to the fungus. MicroRNA-like RNAs (milRNAs) recently identified in A. flavus had been found to be correlated with aflatoxin production conditions, suggesting that the milRNAs might play a role in the regulation of aflatoxin production. In this research, small RNAs were isolated from kernels of maize (resistant Mp719 and susceptible Va35) …