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Urinary Antimicrobial Peptides And The Urinary Microbiota In A Uti-Susceptible Population Of Female Pelvic Floor Surgery Patients, Vanessa Nienhouse
Urinary Antimicrobial Peptides And The Urinary Microbiota In A Uti-Susceptible Population Of Female Pelvic Floor Surgery Patients, Vanessa Nienhouse
Master's Theses
Urinary tract infections (UTI)s are a national priority. Women who undergo surgery for pelvic floor disorders such as pelvic organ prolapse (POP) or urinary incontinence (UI) are at increased risk for UTI, as 10-30% will contract a post-instrumentation UTI (postI-UTI) within six weeks after surgery. Currently, the factors that contribute to the high rate of postI-UTI are unknown, and there is currently no clinical assessment to identify at-risk patients. However, antimicrobial peptides (AMPs) and characteristics of the urinary microbiota have the potential to serve as biomarkers, identifying patients at UTI risk and facilitating clinical prevention studies.
While it was previously …