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Louisiana State University

2016

Antibiotics

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Detection Of Antibiotic Resistance Clostridium Difficile In Lettuce, Yi Han Jan 2016

Detection Of Antibiotic Resistance Clostridium Difficile In Lettuce, Yi Han

LSU Master's Theses

Clostridium difficile (C. difficile) is regarded as the major cause of infectious diarrhea in humans after antimicrobial treatment. C. difficile has been reported to be widely isolated from food animals and meat. The main purpose of this study was to characterize C. difficile isolates from retail fresh vegetable (lettuce), test the antibiotic-resistance property using five common clinical-selected antibiotics (metronidazole, vancomycin, clindamycin, erythromycin, and cefotaxime). Lettuces (grown in California, Arkansas, and Louisiana) were purchased from retail stores. Toxigenic C. difficile was isolated from 13.8% (41/297) of the lettuce samples. Among the toxigenic isolates, 82.9% (34/41) only produce toxin B, and 17.1% …