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Exploring The Biofilm Of Candida Auris As It Relates To Persistence In Clinical Setting And Susceptibility To Antimicrobials, Bethany Butts
Exploring The Biofilm Of Candida Auris As It Relates To Persistence In Clinical Setting And Susceptibility To Antimicrobials, Bethany Butts
Master of Science in Integrative Biology Theses
The rapid rise of drug-resistant pathogens is a global health concern. Known pathogens are acquiring resistance to many commonly used drugs, while new drug-resistant pathogens are emerging. These resistant pathogens are responsible for many healthcare-associated infections (HAI) [1, 2]. Candida auris is among these emerging drug-resistant pathogens, first described in 2009. The CDC labels C. auris at the highest level of global public health threat [3,4]. Effective methods of decolonization and control of the organisms have yet to be established, as it is resistant to many agents used for microbial control. Recent research has found that C. auris has the …
Substrate Utilization Of The Emerging Fungal Pathogen, Candida Auris, And The Antifungal Activity Of Select Essential Oils, Ryan Parker
Master of Science in Integrative Biology Theses
Candida auris is an emerging fungal pathogen that commonly causes nosocomial blood infections in the immunocompromised. Three factors make this emerging pathogen a global threat. First, it is frequently misidentified by commonly used diagnostic platforms. Second, it is able to survive for weeks on fomites. Third, it is almost always drug resistant, sometimes to all three classes of antifungal drugs used to treat Candida infections. The objectives of this study are three-fold. First, two existing methods, population estimation using absorbance-based standard curves and methylene blue viability staining, were investigated as to application in determining Candida auris cell population size and …