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Investigating The Regulation And Role Of P38 Mapk In Collagen-Related Limb Girdle Muscular Dystrophy, Briseida Oceguera-Perez
Investigating The Regulation And Role Of P38 Mapk In Collagen-Related Limb Girdle Muscular Dystrophy, Briseida Oceguera-Perez
Theses and Dissertations
Aging is an expected and normal process across living organisms. It is characterized as a loss of stress resistance, degeneration of tissues, and decline in motor function that happen gradually across lifespan. Susceptibility to neurodegenerative and dystrophic conditions also increase, and unlike aging, are not a normal aspect of lifespan. Discerning the difference between normal and aberrant aging states will give insight into the mechanisms behind the progressive dysfunction shared among organisms. Previous work in our lab has shown that the aging gene p38 MAPK in Drosophila melanogaster plays a significant role in the aging process through its downstream effects …